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CYP1B1 gene

Known as: CP1B, Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 Gene, CYP1B1 
This gene plays a role in eye development, steroid catabolism and xenobiotic metabolism.
National Institutes of Health

Related topics

Related topics

9 relations
CYP1A1 geneCYP1B1 protein, humanEye DevelopmentIron Chelation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Genetic polymorphisms in cytochrome P4501B1 and susceptibility to head and neck cancer.
2008
2008
Association of functionally important polymorphisms in cytochrome P4501B1 with lung cancer.
Highly Cited
2003
Highly Cited
2003
Association of aryl hydrocarbon receptor and cytochrome P4501B1 expressions in human non-small cell lung cancers.
2003
2003
Calpastatin Exon 1B-Derived Peptide, a Selective Inhibitor of Calpain: Enhancing Cell Permeability by Conjugation with Penetratin
Abstract The ubiquitous calpains, u- and m-calpain, have been implicated in essential physiological processes and various… 
Highly Cited
2003
Highly Cited
2003
Phenotype of cytochrome P4501B1 gene (CYP1B1) mutations in Japanese patients with primary congenital glaucoma
Aim: To investigate the phenotypes associated with cytochrome P4501B1 gene (CYP1B1) mutations in Japanese patients with primary… 
Highly Cited
1999
Highly Cited
1999
Identification of a single ancestral CYP1B1 mutation in Slovak Gypsies (Roms) affected with primary congenital glaucoma
Primary congenital glaucoma (PCG) is an autosomal recessive eye disease that occurs at an unusually high frequency in the ethnic… 
Highly Cited
1998
Highly Cited
1998
Sequence analysis and homology modeling suggest that primary congenital glaucoma on 2p21 results from mutations disrupting either the hinge region or the conserved core structures of cytochrome…
We recently reported three truncating mutations of the cytochrome P4501B1 gene (CYP1B1) in five families with primary congenital… 
Highly Cited
1997
Highly Cited
1997
Expression of CYP1B1 in human adult and fetal tissues and differential inducibility of CYP1B1 and CYP1A1 by Ah receptor ligands in human placenta and cultured cells.
Expression of the Ah receptor-regulated cytochrome P4501B1 (CYP1B1) gene was studied in human adult and fetal tissues and cells… 
Highly Cited
1997
Highly Cited
1997
Development of a human lymphoblastoid cell line constitutively expressing human CYP1B1 cDNA: substrate specificity with model substrates and promutagens.
An AHH-1 TK+/- cell derivative was developed that stably expresses human cytochrome P4501B1 (CYP1B1) cDNA in an extrachromosomal… 
Highly Cited
1994
Highly Cited
1994
Complete cDNA sequence of a human dioxin-inducible mRNA identifies a new gene subfamily of cytochrome P450 that maps to chromosome 2.
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