CYP1B1 protein, human

Known as: CYPIB1, EC 1.14.14.1, Cytochrome P450 1B1 
Cytochrome P450 1B1 (543 aa, ~61 kDa) is encoded by the human CYP1B1 gene. This protein plays a role in the metabolism of steroids and xenobiotics.
National Institutes of Health

Papers overview

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2013
2013
BACKGROUND Studies investigating the association between single-nucleotide polymorphisms (SNPs) of the cytochrome P450 1B1… (More)
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2010
2010
The aryl hydrocarbon receptor (AhR) mediates induction of CYP1A1 and CYP1B1 by 2,3,7,8-tetrachlorodibenzo-ρ-dioxin (dioxin) via… (More)
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2009
2009
PURPOSE Mutations in Cytochrome P450 (CYP1B1) are a predominant cause of congenital glaucoma. This study was planned with the aim… (More)
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2008
2008
OBJECTIVE The objective of this study was to examine the biochemical and physical properties of cytochrome P450 1B1 (CYP1B1… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE The carcinogen activator cytochrome P450 1B1 (CYP1B1) is expressed on almost all human tumors with rare expression on… (More)
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2005
2005
Cytochrome P450 1B1 (CYP1B1) and catechol-O-methyltransferase (COMT) are important estrogen-metabolizing enzymes and, thus… (More)
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Highly Cited
2004
Highly Cited
2004
Tobacco smoking and occupation are major risk factors of bladder cancer via exposure to polycyclic aromatic hydrocarbons (PAHs… (More)
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2003
2003
Cytochrome P450 1B1 (CYP1B1) is active in the metabolism of estrogens to reactive catechols and of different procarcinogens… (More)
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Highly Cited
2002
Highly Cited
2002
The endothelium expresses a large repertoire of genes under apparent transcriptional control of biomechanical forces, many of… (More)
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2002
2002
Epidemiological studies indicate that most risk factors for breast cancer are related to reproductive and hormonal factors… (More)
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