CX3C Chemokines

Known as: Chemokines, CX3C, CX3C Chemokine, Delta Chemokine 
Group of chemokines with the first two cysteines separated by three amino acids. CX3C chemokines are chemotactic for natural killer cells, monocytes… (More)
National Institutes of Health

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Biologic DevelopmentCentral Nervous SystemChemotaxisCytokine Gene
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Papers overview

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Review
2016
Review
2016
Effects of CX3CR1 and Fractalkine Chemokines in Amyloid Beta Clearance and p-Tau Accumulation in Alzheimer's Disease (AD) Rodent Models: Is Fractalkine a Systemic Biomarker for AD?
Microglia and astrocytes are the major source of cytokines in Alzheimer,s disease (AD). CX3CR1 is a delta chemokine receptor… (More)
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2012
2012
Soluble factors from T cells inhibiting X4 strains of HIV are a mixture of β chemokines and RNases.
T-cell-derived soluble factors that inhibit both X4 and R5 HIV are recognized as important in controlling HIV. Whereas three… (More)
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2003
2003
Fractalkine transgene induces T-cell-dependent antitumor immunity through chemoattraction and activation of dendritic cells.
Fractalkine (FK, also called neurotactin or CX3CL1) is a CX3C chemokine that can chemoattract T lymphocytes, monocytes and NK… (More)
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Review
2002
Review
2002
Interleukin-8: a very important chemokine of the human airway epithelium.
IN THE LAST TWO AND A HALF DECADES, there has been an explosion of interest in a group of chemotactic cytokines that have… (More)
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2000
2000
Ultrastructure and function of the fractalkine mucin domain in CX(3)C chemokine domain presentation.
Fractalkine (FKN), a CX(3)C chemokine/mucin hybrid molecule on endothelium, functions as an adhesion molecule to capture and… (More)
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2000
2000
Inhibition by IL-12 and IFN-alpha of I-309 and macrophage-derived chemokine production upon TCR triggering of human Th1 cells.
Th1 and Th2 cells, which produce distinct sets of cytokines, differentially express several chemokine receptors that may regulate… (More)
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1998
1998
Cloning and characterization of a new type of mouse chemokine.
We report here the identification and characterization of the mouse homologue of a human CX3C chemokine described by F. Bazan et… (More)
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Highly Cited
1997
Highly Cited
1997
A new class of membrane-bound chemokine with a CX3C motif
Chemokines direct the trafficking of white blood cells in immune surveillance, playing a key role in inflammatory and infectious… (More)
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Highly Cited
1997
Highly Cited
1997
C–C Chemokines Released by Lipopolysaccharide (LPS)-stimulated Human Macrophages Suppress HIV-1 Infection in Both Macrophages and T Cells
Human immunodeficiency virus-1 (HIV-1) expression in monocyte-derived macrophages (MDM) infected in vitro is known to be… (More)
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Highly Cited
1996
Highly Cited
1996
Human recombinant monocyte chemotactic protein and other C-C chemokines bind and induce directional migration of dendritic cells in vitro.
Because dendritic cells (DC) are the most potent antigen-presenting cells involved in many pathophysiological responses, we… (More)
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