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High susceptibility to pemphigus vulgaris due to HLA‐DRB1*14:54 in the Slovak population
An association between pemphigus vulgaris (PV) and class II HLA alleles in the Slovak population is described, the first such study in Slovakia on the ‘high‐resolution level’ and the new HLA allele nomenclature is taken into account.
TNF‐α and IL‐10 gene polymorphisms show a weak association with pemphigus vulgaris in the Slovak population
Pemphigus vulgaris is a rare chronic autoimmune disease of skin and mucous membranes, with several cytokines participating in its development, and its role in susceptibility is not fully understood.
Effect of Mahonia aquifolium active compounds on interleukin-8 production in the human monocytic cell line THP-1.
The effect of the crude extract and of two alkaloid fractions prepared from Mahonia aquifolium on interleukin-8 (IL-8) production in the lipopolysaccharide (LPS)-stimulated human monocytic cell line
[Borrelia burgdorferi antibodies in scleroderma circumscripta, lichen sclerosus et atrophicus, erythema nodosum, granuloma annulare, erythema annulare and chronic urticaria].
It is assumed that in the probands with high titers of antibodies, B. burgdorferi could play a role in the etiology of the given diseases titers and the draft problem could be solved by modern method including PCR with the use of several primers focused on different antigens regarding the certain epidemiologic regions.
Pemphigus vulgaris: a 11-year review.
Although corticosteroids dramatically improved the mortality, and are still considered the first-choice therapy, significant morbidity of the disease and the cortICosteroid treatment still exists.
A randomized, double-blind, placebo-controlled phase 1 study of multiple ascending doses of subcutaneous M1095, an anti-interleukin 17A/F nanobody, in moderate-to-severe psoriasis.
Multiple subcutaneous doses of M1095 showed a favorable safety profile with dose-dependent improvements in psoriasis, and improvements in static Physician's Global Assessment and affected body surface area were seen.
Pemphigus vulgaris: a clinical study of 44 cases over a 20‐year period
  • D. Švecová
  • Medicine
    International journal of dermatology
  • 1 October 2015
Pemphigus vulgaris (PV) is a rare, life‐threatening, autoimmune bullous disease with unpredictable progression and prognosis.
Footwear contact dermatitis from dimethyl fumarate
The aim of this study was to evaluate patients in Slovakia with footwear ACD associated with DMF with regard to clinical manifestations, patch test results, and results of chemical analysis of their footwear.
IVIG therapy in pemphigus vulgaris has corticosteroid‐sparing and immunomodulatory effects
  • D. Švecová
  • Medicine
    The Australasian journal of dermatology
  • 1 May 2016
Intravenous immunoglobulin (IVIG) is a biological agent composed of polyclonal antibodies prepared from a large cohort of human plasma pools. IVIG is increasingly used for the treatment of various
HLA DRB1* and DQB1* alleles are associated with disease severity in patients with pemphigus vulgaris
Pemphigus vulgaris (PV) is a rare autoimmune disease that involves the skin and mucosa. The etiology of PV is multifactorial and includes genetic, environmental, hormonal, and immunological factors.