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High expression of macrophage migration inhibitory factor in human melanoma cells and its role in tumor cell growth and angiogenesis.
Macrophage migration inhibitory factor (MIF) is known to function as a cytokine, hormone, and glucocorticoid-induced immunoregulator. In this study, we reported for the first time that humanExpand
Lactate production and lactate dehydrogenase in the human epidermis.
Several investigators (1, 2, 3, 4) have established that epidermis converts most of the glucose it uses to lactic acid even in the presence of oxygen. This is in contrast to most tissues where lacticExpand
Ultraviolet B radiation upregulates the production of macrophage migration inhibitory factor (MIF) in human epidermal keratinocytes.
Human epidermal cells are capable of secreting various cytokines with immunologic, inflammatory, and proliferative properties. In a previous study, by reverse transcription-polymerase chain reactionExpand
Leukemia Cutis in Acute Myelomonocytic Leukemia: Infiltration to Minor Traumas and Scars
We describe a patient with acute myelomonocytic leukemia who demonstrated leukemic cell infiltration to scratched wounds and scars from trauma. A 65‐year‐old Japanese woman developed low grade fever,Expand
Carbohydrate metabolism in psoriasis: an enzymatic study.
Identification of macrophage migration inhibitory factor (MIF) in human skin and its immunohistochemical localization
The presence and tissue localization of macrophage migration inhibitory factor (MIF) in human skin were examined. Reverse transcription‐polymerase chain reaction analysis revealed that MIF mRNA wasExpand
The measurement of glutathione in human epidermis using glutathione reductase.
A sulfhydryl-containing small molecule responsible for the inhibition of melanin synthesis and present within the epidermis was postulated by Rothman in 1946 (1). In most tissues the main non-proteinExpand
Macrophage migration inhibitory factor is an essential immunoregulatory cytokine in atopic dermatitis.
Macrophage migration inhibitory factor (MIF) is one of the immunoregulatory cytokines involved in T-cell activation and delayed-type hypersensitivity. To elucidate involvement of this cytokine in theExpand
Generalized pustular psoriasis in Japan: two distinct groups formed by differences in symptoms and genetic background.
A multi-center study for investigating generalized pustular psoriasis was carried out in Japan in order to clarify the prevalence, the etiology, and the standard therapy. Through questionnaires, 541Expand
High macrophage migration inhibitory factor (MIF) serum levels associated with extended psoriasis.