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CUL4A gene

Known as: CUL4A, CULLIN 4A, Cullin 4A Gene 
This gene is involved in protein degradation. It also plays a role in cell cycle arrest and DNA repair.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
  • Xi Li, D. Lu, +5 authors Y. Gong
  • The Journal of Biological Chemistry
  • 2011
  • Corpus ID: 24495026
Cullin 4B (CUL4B) is a scaffold protein that assembles cullin-RING ubiquitin ligase (E3) complexes. Recent studies have revealed… Expand
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Highly Cited
2008
Highly Cited
2008
Previous reports showed that chromatin-associated PCNA couples DNA replication with Cul4-DDB1Cdt2-dependent proteolysis of the… Expand
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Highly Cited
2007
Highly Cited
2007
Human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) has been shown to cause G2 cell cycle arrest in human cells by… Expand
Highly Cited
2007
Highly Cited
2007
Cullin-based E3 ligases are a large family of multi-subunit ubiquitin ligases with diverse cellular functions, including the… Expand
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Highly Cited
2006
Highly Cited
2006
Posttranslational histone modifications play important roles in transcription and other chromatin-based processes. Compared to… Expand
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Highly Cited
2006
Highly Cited
2006
The DDB1-Cul4A ubiquitin ligase complex promotes protein ubiquitination in diverse cellular functions and is reprogrammed by the… Expand
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Highly Cited
2006
Highly Cited
2006
As erythroid progenitors differentiate into precursors and finally mature red blood cells, lineage-specific genes are induced… Expand
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Highly Cited
2004
Highly Cited
2004
Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse… Expand
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Highly Cited
2004
Highly Cited
2004
Arabidopsis thaliana De-etiolated-1 (AtDET1) is a highly conserved protein, with orthologs in vertebrate and invertebrate… Expand
Review
2004
Review
2004
This review summarizes recent advances concerning the Nedd8 regulatory pathway in four areas. One, substantial progress has been… Expand
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