CUL4A gene

Known as: CUL4A, CULLIN 4A, Cullin 4A Gene 
This gene is involved in protein degradation. It also plays a role in cell cycle arrest and DNA repair.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2016
024619992016

Papers overview

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2014
2014
CUL4A has been proposed as oncogene in several types of human cancer, but its clinical significance and functional role in human… (More)
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2014
2014
The CUL4A E3 ubiquitin ligase is involved in the regulation of many cellular processes and its amplification and/or… (More)
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2013
2013
CUL4A encodes a core component of a cullin-based E3 ubiquitin ligase complex that regulates many critical processes such as cell… (More)
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2012
2012
Thalidomide is experimentally used to treat various human cancers; however, clinical responses to thalidomide are sporadic. Here… (More)
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2009
2009
The human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) genomes encode several auxiliary proteins that… (More)
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2009
2009
Breast cancer subtypes exhibit different genomic aberration patterns with a tendency for high-level amplifications in distinct… (More)
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Highly Cited
2008
Highly Cited
2008
By removing UV-induced lesions from DNA, the nucleotide excision repair (NER) pathway preserves the integrity of the genome. The… (More)
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2007
2007
Damage DNA binding protein 2 (DDB2) has a high affinity for UV-damaged DNA and has been implicated in the initial steps of global… (More)
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2006
2006
Functional defect in DNA damage binding (DDB) activity has a direct relationship to decreased nucleotide excision repair (NER… (More)
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Highly Cited
2002
Highly Cited
2002
We carried out molecular cytogenetic characterization of 11 cell lines derived from hepatocellular carcinomas (HCCs) and 51… (More)
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