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CUL4A gene

Known as: CUL4A, CULLIN 4A, Cullin 4A Gene 
This gene is involved in protein degradation. It also plays a role in cell cycle arrest and DNA repair.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
ABSTRACT The human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) genomes encode several auxiliary proteins… 
Highly Cited
2008
Highly Cited
2008
Previous reports showed that chromatin-associated PCNA couples DNA replication with Cul4-DDB1Cdt2-dependent proteolysis of the… 
Highly Cited
2007
Highly Cited
2007
Human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) has been shown to cause G2 cell cycle arrest in human cells by… 
Highly Cited
2007
Highly Cited
2007
Cullin-based E3 ligases are a large family of multi-subunit ubiquitin ligases with diverse cellular functions, including the… 
Highly Cited
2006
Highly Cited
2006
The CUL4-ROC1 E3 ligase complex regulates genome stability, replication, and cell cycle progression. A novel WD40 domain… 
Highly Cited
2004
Highly Cited
2004
Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse… 
Highly Cited
2004
Highly Cited
2004
Arabidopsis thaliana De-etiolated-1 (AtDET1) is a highly conserved protein, with orthologs in vertebrate and invertebrate… 
Review
2004
Review
2004
This review summarizes recent advances concerning the Nedd8 regulatory pathway in four areas. One, substantial progress has been…