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CUL4A gene

Known as: CUL4A, CULLIN 4A, Cullin 4A Gene 
This gene is involved in protein degradation. It also plays a role in cell cycle arrest and DNA repair.
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
The ubiquitin ligase CUL4A has been implicated in tumorigenesis, but its contributions to progression and metastasis have not… Expand
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Highly Cited
2009
Highly Cited
2009
It is intuitively obvious that the ability of a cell to repair DNA damage is saturable, either by limitation of enzymatic… Expand
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Highly Cited
2009
Highly Cited
2009
ABSTRACT The human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) genomes encode several auxiliary proteins… Expand
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Highly Cited
2009
Highly Cited
2009
The cellular response to hypoxia involves several signalling pathways that mediate adaptation and survival. REDD1 (regulated in… Expand
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Highly Cited
2009
Highly Cited
2009
IntroductionBreast cancer subtypes exhibit different genomic aberration patterns with a tendency for high-level amplifications in… Expand
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Highly Cited
2006
Highly Cited
2006
As erythroid progenitors differentiate into precursors and finally mature red blood cells, lineage-specific genes are induced… Expand
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Highly Cited
2006
Highly Cited
2006
Posttranslational histone modifications play important roles in transcription and other chromatin-based processes. Compared to… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT DDB1, a subunit of the damaged-DNA binding protein DDB, has been shown to function also as an adaptor for Cul4A, a… Expand
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Highly Cited
2004
Highly Cited
2004
Arabidopsis thaliana De-etiolated-1 (AtDET1) is a highly conserved protein, with orthologs in vertebrate and invertebrate… Expand
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Highly Cited
2004
Highly Cited
2004
Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse… Expand
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