cullin 4A

Known as: Cullin Homolog 4A, CUL-4A, CUL4A 
Cullin-4A (759 aa, ~88 kDa) is encoded by the human CUL4A gene. This protein is involved in both DNA repair and protein ubiquitination.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2017
05101519982017

Papers overview

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2011
2011
The Cullin-RING ubiquitin-ligase CRL4 controls cell cycle and DNA damage checkpoint response and ensures genomic integrity… (More)
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2010
2010
The human immunodeficiency virus type 1 (HIV-1) accessory protein, Vpr, interacts with several host cellular proteins including… (More)
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2006
Highly Cited
2006
Xeroderma pigmentosum (XP) complementation group E gene product, damaged DNA-binding protein 2 (DDB2), is a subunit of the DDB… (More)
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2006
Highly Cited
2006
Protein ubiquitination is a common form of post-translational modification that regulates a broad spectrum of protein substrates… (More)
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2005
2005
Xeroderma pigmentosum (XP) is a genetic disease characterized by hypersensitivity to UV irradiation and high incidence of skin… (More)
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2004
Highly Cited
2004
Arabidopsis thaliana De-etiolated-1 (AtDET1) is a highly conserved protein, with orthologs in vertebrate and invertebrate… (More)
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2001
Highly Cited
2001
The damaged-DNA binding protein DDB consists of two subunits, DDB1 (127 kDa) and DDB2 (48 kDa). Mutations in the DDB2 subunit… (More)
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Highly Cited
2001
Highly Cited
2001
Cul-4A, which encodes a member of the cullin family subunit of ubiquitin-protein ligases, is expressed at abnormally high levels… (More)
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Highly Cited
1999
Highly Cited
1999
The damaged DNA-binding protein (DDB) is believed to be involved in DNA repair, and it has been linked to the repair deficiency… (More)
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1998
Highly Cited
1998
NEDD8 is a ubiquitin (Ub)-like protein. Here we report a novel ubiquitinylation-related pathway for modification by NEDD8. NEDD8… (More)
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