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CT 112

Known as: CT-112 
National Institutes of Health

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Papers overview

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1998
1998
Diabetic-like corneal sensitivity loss in galactose-fed rats ameliorated with aldose reductase inhibitors.
This study investigated whether diabetic-like corneal sensory deficits occur in the galactose-fed rat model of diabetic ocular… 
1995
1995
The influence of a peptide sequence from PF-4 (CT-112) on type II collagen-induced arthritis in mice
CT-112 is a PF-4 derived octapeptide with the sequence T T S Q V R P R . CT-112 has been demonst ra ted to possess ant i inf… 
1995
1995
Anti-inflammatory activity of an orally active peptide sequence from PF-4 on acute inflammation and DTH
CT-112 is an oc tapep t ide wi th the sequence T T S Q V R P R . This sequence is found in at least h u m a n p la te le t fac… 
Review
1994
Review
1994
Drugs designed to maintain the transparence of the ocular lens
Summary— Research into the biological basis of lens transparency has demonstrated the implication of lens sugar stress in the… 
1994
1994
CT-112 and Diabetic Keratopathy
1991
1991
Penetration and binding of aldose-reductase inhibitors in the lens.
Diffusion, partitioning, and binding of two aldose-reductase inhibitors (ARI) in the rat lens were investigated under in vitro… 
1990
1990
In vitro study of aldose reductase inhibitor concentrations in the lens and inhibitory effect on sugar alcohol accumulation.
Rat lenses were cultured in a medium containing either 30mM xylose or 30mM glucose. Inhibitory effects of two aldose reductase… 
1989
1989
Intraocular penetration of CT-112, an aldose reductase inhibitor, following topical instillation.
Intraocular penetration of 5-(3-ethoxy-4-pentyloxyphenyl)thiazolidine-2,4-dione (CT-112), an aldose reductase inhibitor, was… 
1988
1988
Aldose reductase inhibitor (CT-112) eyedrops for diabetic corneal epitheliopathy.
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