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Screening for dry eye with newly developed ocular surface thermographer.
PURPOSE To evaluate the newly developed Ocular Surface Thermographer (TOMEY Corporation) for dry eye screening. DESIGN Prospective, controlled study. METHODS We studied 30 eyes of 30 patientsExpand
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A randomized, placebo-controlled clinical trial of tacrolimus ophthalmic suspension 0.1% in severe allergic conjunctivitis.
AIMS To examine the efficacy of tacrolimus ophthalmic suspension 0.1% in treating severe allergic conjunctivitis. METHODS This was a multicenter, randomized, double-masked, placebo-controlledExpand
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Development and validation of the Dry Eye-Related Quality-of-Life Score questionnaire.
IMPORTANCE A validated questionnaire that assesses symptoms and the effect of dry eye disease (DED) on the patient's daily life is needed to evaluate the condition. OBJECTIVE To develop andExpand
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Tear Film Stability Analysis System: Introducing a New Application for Videokeratography
Purpose To review our previous studies regarding the development of a tear stability analysis system (TSAS) using videokeratography and the clinical application of TSAS for evaluation of tear filmExpand
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Association of Toll-like receptor 4 gene polymorphisms in Japanese subjects with primary open-angle, normal-tension, and exfoliation glaucoma.
PURPOSE To determine whether polymorphisms in the Toll-like receptor 4 (TLR4) gene are associated with primary open-angle glaucoma (POAG), normal-tension glaucoma (NTG), and exfoliation glaucomaExpand
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In vivo confocal microscopic evidence of keratopathy in patients with pseudoexfoliation syndrome.
PURPOSE To measure the density of cells in different layers of the cornea and to determine whether morphologic changes of the subbasal corneal nerve plexus are present in eyes with theExpand
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Cytomegalovirus as an etiologic factor in corneal endotheliitis.
PURPOSE To investigate clinical manifestations and response to antiviral therapy of 8 patients with cytomegalovirus (CMV)-induced corneal endotheliitis who were diagnosed and treated at 2 universityExpand
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Marx line: fluorescein staining line on the inner lid as indicator of meibomian gland function.
PURPOSE To determine whether the location of a fluorescein-stained line, the Marx line (ML), which runs along the inner eyelid, is correlated with meibomian gland function. DESIGN ProspectiveExpand
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A large prospective observational study of novel cyclosporine 0.1% aqueous ophthalmic solution in the treatment of severe allergic conjunctivitis.
PURPOSE To evaluate the effectiveness and safety of a novel cyclosporine 0.1% aqueous ophthalmic solution in a large population with vernal keratoconjunctivitis (VKC) and atopic keratoconjunctivitisExpand
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Clinical features and management of cytomegalovirus corneal endotheliitis: analysis of 106 cases from the Japan corneal endotheliitis study
Aims The purpose of this study is to elucidate the clinical manifestations and the current treatment status of cytomegalovirus (CMV) endotheliitis via a large case series obtained from a nationalExpand
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