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CRLF2 protein, human

Known as: Cytokine Receptor-Like 2, CRL2 protein, human, IL-XR 
Cytokine receptor-like factor 2 (371 aa, ~42 kDa) is encoded by the human CRLF2 gene. This protein is involved in the mediation of both cytokine… 
National Institutes of Health

Related topics

Related topics

14 relations
CRLF2 geneCytokine Receptor GeneCytokine SignalingCytokine Signaling Process

Broader (1)

Receptors, Cytokine

Papers overview

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2018
2018
TSLP Protects Corneas From Pseudomonas aeruginosa Infection by Regulating Dendritic Cells and IL-23-IL-17 Pathway
Purpose We sought to determine the role of epithelium-produced thymic stromal lymphopoietin (TSLP) and its underlying mechanisms… 
2017
2017
Human thymic stromal lymphopoietin promotes the proliferation and invasion of cervical cancer cells by downregulating microRNA-132 expression.
Thymic stromal lymphopoietin (TSLP), produced by cervical cancer (CC) cells, promotes angiogenesis, and the recruitment and… 
2015
2015
Murine allergic rhinitis and nasal Th2 activation are mediated via TSLP- and IL-33-signaling pathways.
Thymic stromal lymphopoietin (TSLP) and IL-33 are epithelium-derived proallergic cytokines that contribute to allergic diseases… 
2015
2015
Down-Regulation of miR-146a Expression Induces Allergic Conjunctivitis in Mice by Increasing TSLP Level
Background Pollen is the most common aeroallergen to cause conjunctivitis. In this study, we established a short ragweed (SRW… 
2014
2014
A Critical Role for Thymic Stromal Lymphopoietin in Nickel-Induced Allergy in Mice
Ni is the most frequent cause of contact allergy induced by metals. However, the underlying mechanism of this induction is… 
2013
2013
Expression analysis and specific blockade of the receptor for human thymic stromal lymphopoietin (TSLP) by novel antibodies to the human TSLPRα receptor chain.
2012
2012
Genetic resistance to JAK 2 enzymatic inhibitors is overcome by HSP 90 inhibition
The Rockefeller University Press $30.00 J. Exp. Med. Vol. 209 No. 2 259-273 www.jem.org/cgi/doi/10.1084/jem.20111694 259 Janus… 
2011
2011
Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias
IL-7R  (IL7R) is required for normal lym-phoid development (Peschon et al., 1994). Loss-of-function mutations in this receptor… 
2010
2010
Rearrangement of CRLF 2 is associated with mutation of JAK kinases , alteration of IKZF 1 , Hispanic / Latino ethnicity , and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia *
1University of New Mexico Cancer Center and Departments of Pathology and Internal Medicine, University of New Mexico, Albuquerque… 
2001
2001
Identification of a novel type I cytokine receptor CRL2 preferentially expressed by human dendritic cells and activated monocytes.
From a human dendritic cell (DC) cDNA library, we identified a novel type I cytokine receptor, designated as cytokine receptor… 
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