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CLEC7A gene

Known as: hDectin-1, C-type Lectin Domain Family 7, Member A Gene, DECTIN 1 
This gene plays a role in the innate immune response.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
The Mycobiome In the past few years, much attention has been given to the trillions of bacterial inhabitants in our guts and the… Expand
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Highly Cited
2009
Highly Cited
2009
Mucocutaneous fungal infections are typically found in patients who have no known immune defects. We describe a family in which… Expand
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Review
2009
Review
2009
The β-glucan receptor Dectin-1 is an archetypical non-toll-like pattern recognition receptor expressed predominantly by myeloid… Expand
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Highly Cited
2008
Highly Cited
2008
Candida albicans, a clinically important dimorphic fungal pathogen that can evade immune attack by masking its cell wall β-glucan… Expand
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Highly Cited
2007
Highly Cited
2007
Beta-glucan is one of the most abundant polysaccharides in fungal pathogens, yet its importance in antifungal immunity is unclear… Expand
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Highly Cited
2007
Highly Cited
2007
β-Glucan is one of the most abundant polysaccharides in fungal pathogens, yet its importance in antifungal immunity is unclear… Expand
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Review
2006
Review
2006
  • G. Brown
  • Nature Reviews Immunology
  • 2006
  • Corpus ID: 1310559
Dectin-1 is a natural killer (NK)-cell-receptor-like C-type lectin that is thought to be involved in innate immune responses to… Expand
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Highly Cited
2006
Highly Cited
2006
Pattern recognition receptors (PRRs) play an essential role in a macrophage's response to mycobacterial infections. However, how… Expand
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Highly Cited
2006
Highly Cited
2006
Fungal pathogens can be recognized by the immune system via their β-glucan, a potent proinflammatory molecule that is present at… Expand
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Highly Cited
2002
Highly Cited
2002
Zymosan is a β-glucan– and mannan-rich particle that is widely used as a cellular activator for examining the numerous responses… Expand
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