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CLEC7A protein, human

Known as: hDectin-1, C-type lectin domain family 7, member A, human, Dectin 1 
C-type lectin domain family 7 member A (247 aa, ~28 kDa) is encoded by the human CLEC7A gene. This protein plays a role in the innate immune response… 
National Institutes of Health

Related topics

Related topics

4 relations
CLEC7A geneImmune System Processesdectin 1

Broader (1)

Lectins, C-Type

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
FcεRI γ-Chain Negatively Modulates Dectin-1 Responses in Dendritic Cells
The inhibitory effect of immunoreceptor tyrosine-based activation motif (ITAM)-containing adapters DAP12 and FcεRI γ-chain (FcR… 
2017
2017
Dectin-1 Compromises Innate Responses and Host Resistance against Neospora caninum Infection
Neospora caninum is an intracellular protozoan parasite that has drawn increasing interest due to its association with worldwide… 
2015
2015
Recognition of Candida albicans by Dectin-1 induces mast cell activation.
2014
2014
A Chitin-Like Component on Sclerotic Cells of Fonsecaea pedrosoi Inhibits Dectin-1-Mediated Murine Th17 Development by Masking β-Glucans
Fonsecaea pedrosoi (F. pedrosoi), a major agent of chromoblastomycosis, has been shown to be recognized primarily by C-type… 
2011
2011
Novel approach for interleukin‐23 up‐regulation in human dendritic cells and the impact on T helper type 17 generation
Interleukin‐23 (IL‐23) is important for T helper type 17 (Th17) responses and strategies to regulate IL‐23 in human dendritic… 
2011
2011
Hot water extract of the sclerotium of Polyporus rhinocerus Cooke enhances the immune functions of murine macrophages.
Treatment of hot water extract of the sclerotium of Polyporus rhinocerus (PRW) with murine macrophages including RAW 264.7 cell… 
Highly Cited
2010
Highly Cited
2010
Distinct roles of complement receptor 3, Dectin‐1, and sialic acids in murine macrophage interaction with Histoplasma yeast
The yeast cells of dimorphic fungal pathogen Histoplasma reside primarily within the macrophages of an infected host; the… 
Highly Cited
2009
Highly Cited
2009
Zymosan treatment of mouse mast cells enhances dectin-1 expression and induces dectin-1-dependent reactive oxygen species (ROS) generation.
Review
2006
Review
2006
Toll-like receptor signaling mechanisms involved in dendritic cell activation: potential therapeutic control of T cell polarization.
Dendritic cells (DCs) represent a bridge between innate and adaptive immunity, being the maturation process dependent on the… 
1994
1994
CD11b/CD18 integrin and a beta-glucan receptor act in concert to induce the synthesis of platelet-activating factor by monocytes.
We determined the mechanism by which opsonized zymosan particles, which are derived from yeast and composed of carbohydrate… 
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