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CLCA2 protein, human

Known as: Calcium-Sensitive Chloride Channel 2, hCLCA2, CaCC-3 
Calcium-activated chloride channel regulator 2 (943 aa, ~104 kDa) is encoded by the human CLCA2 gene. This protein is involved in chloride ion… 
National Institutes of Health

Papers overview

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2013
2013
The epithelial to mesenchymal transition (EMT) is a developmental program in which epithelial cells downregulate their cell-cell… 
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Highly Cited
2012
Highly Cited
2012
Transition between epithelial and mesenchymal states is a feature of both normal development and tumor progression. We report… 
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Highly Cited
2009
Highly Cited
2009
hCLCA2 is frequently down-regulated in breast cancer and is a candidate tumor suppressor gene. We show here that the hCLCA2 gene… 
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Highly Cited
2004
Highly Cited
2004
The calcium-activated chloride channel gene family is clustered in the 1p31 region, which is frequently deleted in sporadic… 
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Highly Cited
2003
Highly Cited
2003
Human airway epithelia express Ca2+-activated Cl− channels (CaCC) that are activated by extracellular nucleotides (ATP and UTP… 
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Highly Cited
2003
Highly Cited
2003
CLCA (chloride channel, calcium-activated) proteins are novel pulmonary vascular addresses for blood-borne, lung-metastatic… 
Highly Cited
2001
Highly Cited
2001
Adhesion of blood-borne cancer cells to the endothelium is a critical determinant of organ-specific metastasis. Here we show that… 
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Highly Cited
2001
Highly Cited
2001
In whole‐cell recordings from HaCaT keratinocytes, ATP, bradykinin, and histamine caused a biphasic change of the membrane… 
Review
2000
Review
2000
1. In the present brief review, we describe some of the molecular and functional characteristics of a novel mammalian family of… 
Highly Cited
1999
Highly Cited
1999
The CLCA family of Ca2+-activated Cl- channels has recently been discovered, with an increasing number of closely related members… 
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