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Chloride Channels

Known as: Chloride Channel, Channels, Chloride, Chloride Ion Channels 
Cell membrane glycoproteins that form channels to selectively pass chloride ions. Nonselective blockers include FENAMATES; ETHACRYNIC ACID; and… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Drug repositioning is a highly studied alternative strategy to discover and develop anticancer drugs. This drug development… Expand
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Review
2009
Review
2009
Chloride channels represent a relatively under-explored target class for drug discovery as elucidation of their identity and… Expand
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Highly Cited
2008
Highly Cited
2008
Calcium-activated chloride channels (CaCCs) are major regulators of sensory transduction, epithelial secretion, and smooth muscle… Expand
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Highly Cited
2008
Highly Cited
2008
Calcium (Ca2+)-activated chloride channels are fundamental mediators in numerous physiological processes including… Expand
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Highly Cited
2008
Highly Cited
2008
Calcium-dependent chloride channels are required for normal electrolyte and fluid secretion, olfactory perception, and neuronal… Expand
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Review
2006
Review
2006
CFTR chloride channels are encoded by the gene mutated in patients with cystic fibrosis. These channels belong to the superfamily… Expand
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Highly Cited
2003
Highly Cited
2003
ClC channels conduct chloride (Cl–) ions across cell membranes and thereby govern the electrical activity of muscle cells and… Expand
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Highly Cited
2002
Highly Cited
2002
The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation… Expand
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Highly Cited
2001
Highly Cited
2001
Chloride channels play important roles in the plasma membrane and in intracellular organelles. Mice deficient for the… Expand
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Highly Cited
1995
Highly Cited
1995
EXCITATORY amino-acid transporters (EAATs) in the central nervous system maintain extracellular glutamate concentrations below… Expand
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