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Chloride Channels
Known as:
Chloride Channel
, Channels, Chloride
, Chloride Ion Channels
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Cell membrane glycoproteins that form channels to selectively pass chloride ions. Nonselective blockers include FENAMATES; ETHACRYNIC ACID; and…
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National Institutes of Health
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Related topics
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42 relations
Narrower (33)
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In Blood
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antagonists & inhibitors
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Broader (1)
Ion Channel
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Chloride channels: often enigmatic, rarely predictable.
Charity G. Duran
,
Christopher H. Thompson
,
Qinghuan Xiao
,
H. Hartzell
Annual Review of Physiology
2010
Corpus ID: 263489591
Until recently, anion (Cl(-)) channels have received considerably less attention than cation channels. One reason for this may be…
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Review
2008
Review
2008
CLC Chloride Channels and Transporters: From Genes to Protein Structure, Pathology and Physiology
T. Jentsch
Critical reviews in biochemistry and molecular…
2008
Corpus ID: 1292192
ABSTRACT CLC genes are expressed in species from bacteria to human and encode Cl−-channels or Cl−/H+-exchangers. CLC proteins…
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Review
2005
Review
2005
Calcium-activated chloride channels.
C. Hartzell
,
Ilva Putzier
,
J. Arreola
Annual Review of Physiology
2005
Corpus ID: 16873388
Calcium-activated chloride channels (CaCCs) play important roles in cellular physiology, including epithelial secretion of…
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Highly Cited
2005
Highly Cited
2005
Loss of the chloride channel ClC‐7 leads to lysosomal storage disease and neurodegeneration
D. Kasper
,
R. Planells-Cases
,
+9 authors
T. Jentsch
EMBO Journal
2005
Corpus ID: 9426811
ClC‐7 is a chloride channel of late endosomes and lysosomes. In osteoclasts, it may cooperate with H+‐ATPases in acidifying the…
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Highly Cited
2003
Highly Cited
2003
Gating the Selectivity Filter in ClC Chloride Channels
R. Dutzler
,
E. Campbell
,
R. MacKinnon
Science
2003
Corpus ID: 41474053
ClC channels conduct chloride (Cl–) ions across cell membranes and thereby govern the electrical activity of muscle cells and…
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Review
2003
Review
2003
Amazing chloride channels: an overview.
B. Nilius
,
G. Droogmans
Acta Physiologica Scandinavica
2003
Corpus ID: 32070665
AIM This review describes molecular and functional properties of the following Cl- channels: the ClC family of voltage-dependent…
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Highly Cited
2002
Highly Cited
2002
The vitelliform macular dystrophy protein defines a new family of chloride channels
Hui Sun
,
T. Tsunenari
,
K. Yau
,
J. Nathans
Proceedings of the National Academy of Sciences…
2002
Corpus ID: 13569402
Vitelliform macular dystrophy (VMD/Best disease; MIM*153700) is an early-onset autosomal dominant disorder in which accumulation…
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Highly Cited
1997
Highly Cited
1997
avr‐15 encodes a chloride channel subunit that mediates inhibitory glutamatergic neurotransmission and ivermectin sensitivity in Caenorhabditis elegans
J. Dent
,
M. Davis
,
L. Avery
EMBO Journal
1997
Corpus ID: 26407722
Ivermectin is a widely used anthelmintic drug whose nematocidal mechanism is incompletely understood. We have used Caenorhabditis…
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Highly Cited
1996
Highly Cited
1996
Identification of a Drosophila melanogaster Glutamate-gated Chloride Channel Sensitive to the Antiparasitic Agent Avermectin*
D. Cully
,
P. Paress
,
Ken K. Liu
,
J. Schaeffer
,
J. P. Arena
Journal of Biological Chemistry
1996
Corpus ID: 19757684
Glutamate-gated chloride channels, members of the ligand-gated ion channel superfamily, have been shown in nematodes and in…
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Highly Cited
1992
Highly Cited
1992
A chloride channel widely expressed in epithelial and non-epithelial cells
A. Thiemann
,
S. Gründer
,
M. Pusch
,
T. Jentsch
Nature
1992
Corpus ID: 4254798
CHLORIDE channels have several functions, including the regulation of cell volume1,2, stabilizing membrane potential3,4, signal…
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