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CHEK1 gene

Known as: CHK1 Checkpoint Homolog (S.Pombe) Gene, CHEK1, CHK1 
This gene is involved in the negative regulation of cell growth.
National Institutes of Health

Related topics

Related topics

6 relations
CHEK1 protein, humanCheckpoint kinase 1Negative Regulation of Cell CyclePhosphorylation

Papers overview

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2017
2017
BNOS 2016 Abstracts: Poster Presentations.
AbstractPaediatric glioblastomas (pGBM) are biologically distinct from adults, and are in part defined by highly recurrent… 
2014
2014
Abstract 5179: Context-specific dependence of ovarian cancer on IKKε and CHEK1
Background: The IκB kinase, IKKe, was previously identified as an oncogene in breast cancer and was associated with poor clinical… 
2014
2014
Identifying New Genes for Inherited Breast Cancer by Exome Sequencing
Identifying New Genes for Inherited Breast Cancer by Exome Sequencing Cailyn H Spurrell Chair of the Supervisory Committee… 
2014
2014
FU resistance abrogates the amplified cytotoxic effects induced by inhibiting checkpoint kinase 1 in p 53 ‐ mutated colon cancer cells
the emergence of chemoresistance is a major limitation of current cancer therapies, and checkpoint kinase (chk1) 1 positively… 
2011
2011
Preclinical Development Context Dependence of Checkpoint Kinase 1 as a Therapeutic Target for Pancreatic Cancers Deficient in the BRCA 2 Tumor Suppressor
Inherited mutations in the tumor suppressor BRCA2 are predisposed to pancreatic adenocarcinomas, which carry activating mutations…