CDT1 Gene

Known as: RIS2, CDT1, DNA Replication Factor Gene 
This gene is involved in pre-initiation of DNA replication.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2017
051020012017

Papers overview

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Highly Cited
2011
Highly Cited
2011
Loss of NEDD8-activating enzyme (NAE) function by siRNA knockdown or inhibition by the small molecule NAE inhibitor MLN4924 leads… (More)
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2011
2011
Several proteins, including the replication licensing factor CDT1 and the histone methyltransferase SET8, are targeted for… (More)
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Highly Cited
2009
Highly Cited
2009
Proliferation in the nonpregnant human breast is highest in the luteal phase of the menstrual cycle when serum progesterone… (More)
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Highly Cited
2008
Highly Cited
2008
The faithful replication of genomic DNA is crucial for maintaining genome stability. In eukaryotes, DNA rereplication is… (More)
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Highly Cited
2006
Highly Cited
2006
The CUL4 (cullin 4) proteins are the core components of a new class of ubiquitin E3 ligases that regulate cell cycle, DNA… (More)
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Highly Cited
2005
Highly Cited
2005
In late mitosis and G1, Mcm2-7 are assembled onto replication origins to 'license' them for initiation. At other cell cycle… (More)
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Highly Cited
2004
Highly Cited
2004
Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse… (More)
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Highly Cited
2004
Highly Cited
2004
Licensing origins for replication upon completion of mitosis ensures genomic stability in cycling cells. Cdt1 was recently… (More)
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Highly Cited
2003
Highly Cited
2003
Genomic integrity is maintained by checkpoints that guard against undesired replication after DNA damage. Here, we show that CDT1… (More)
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Highly Cited
2002
Highly Cited
2002
The expression of a gene, designated as Retroviral insertion site (Ris)2, was activated by retroviral DNA integration in an… (More)
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