DNA Replication Factor

Known as: DNA Replication Factor Cdt1, hCdt1, CDT1 
DNA replication factor Cdt1 (546 aa, ~60 kDa) is encoded by the human CDT1 gene. This protein plays a role in protein-protein interactions that are… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Break-induced replication (BIR) is an efficient homologous recombination (HR) pathway employed to repair a DNA double-strand… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2008
Highly Cited
2008
The faithful replication of genomic DNA is crucial for maintaining genome stability. In eukaryotes, DNA rereplication is… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
In late mitosis and G1, Mcm2-7 are assembled onto replication origins to 'license' them for initiation. At other cell cycle… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Geminin is an unstable inhibitor of DNA replication that negatively regulates the licensing factor CDT1 and inhibits pre… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Licensing of replication origins is carefully regulated in a cell cycle to maintain genome integrity. Using an in vivo… (More)
Is this relevant?
Highly Cited
2004
Highly Cited
2004
In eukaryotic cells, the function of DNA replication licensing components (Cdc6 and Cdt1, among others) is crucial for cell… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
DNA replication initiation is tightly controlled so that each origin only fires once per cell cycle. Cell cycle-dependent Cdt1… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
S-phase onset is controlled, so that it occurs only once every cell cycle. DNA is licensed for replication after mitosis in G(1… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
To maintain genome stability in eukaryotic cells, DNA is licensed for replication only after the cell has completed mitosis… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2000
Highly Cited
2000
We identified a Drosophila gene, double parked (dup), that is essential for DNA replication and belongs to a new family of… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?