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DNA Replication Factor

Known as: DNA Replication Factor Cdt1, hCdt1, CDT1 
DNA replication factor Cdt1 (546 aa, ~60 kDa) is encoded by the human CDT1 gene. This protein plays a role in protein-protein interactions that are… 
National Institutes of Health

Related topics

Related topics

13 relations
CDT1 GeneCDT1 wt AlleleCell Cycle ControlDNA Replication

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Inhibition of NEDD 8-Activating Enzyme Induces Rereplication and Apoptosis in Human Tumor Cells Consistent with Deregulating CDT 1 Turnover
Loss of NEDD8-activating enzyme (NAE) function by siRNA knockdown or inhibition by the small molecule NAE inhibitor MLN4924 leads… 
2010
2010
Analysis of the architecture and function of the nuclear DNA replication apparatus in Trypanosoma brucei
DNA replication is central to the propagation of life and initiates by the designation of genome sequences as origins, where… 
2010
2010
IRIDIUM CATALYZED C-H ACTIVATION/BORYLATION OF AROMATIC/ HETEROAROMATIC SUBSTRATES AND ITS APPLICATION IN SMALL MOLECULE SYNTHESIS
IRIDIUM CATALYZED C–H ACTIVATION/BORYLATION OF AROMATIC/ HETEROAROMATIC SUBSTRATES AND ITS APPLICATION IN SMALL MOLECULE… 
2009
2009
Identification of the functional domains involved in the interaction between human Cdt1 and Mcm6
2006
2006
DTL / CDT 2 is essential for both CDT 1 regulation and the early G 2 / M checkpoint
Checkpoint genes maintain genomic stability by arresting cells after DNA damage. Many of these genes also control cell cycle… 
2006
2006
[Mutation analysis of FOXL2 in Chinese patients with blepharophimosis-ptosis-epicanthus inversus syndrome].
  • Y. QiY. Li Ya-ping Liu
  • [Zhonghua yan ke za zhi] Chinese journal of…
  • 2006
  • Corpus ID: 42290581
OBJECTIVE To identify the genetic mutation in two Chinese families and 6 sporadic patients with belpharophimosis-ptosis… 
2003
2003
Erratum: Radiation-mediated proteolysis of CDT1 by CUL4–ROC1 and CSN complexes constitutes a new checkpoint
In Higa L. A. A. et al. Nature Cell Biol. 5, 1008–1015 (2003), the last line of the legend to Fig. 3e “monitor CDT1, CHK2 and… 
1997
1997
[The anti-arrhythmic effect of the selective sigma-receptor antagonist DuP 734 [1-(cyclopropylmethyl)-4-(2'-(4''-fluorophenyl)-2'-oxoethyl)piper idine HBr]].
It was demonstrated on models of epinephrine-, CaCl2-, and aconitine-induced arrhythmias that the sigma-receptor antagonist… 
1993
1993
Mosaic dup (9p) diagnosed by fluorescence in situ hybridization (FISH).
We describe a girl with some manifestations of the dup (9p) syndrome. High-resolution Giemsa-banded karyotype of her lymphocytes… 
Highly Cited
1975
Highly Cited
1975
Chromosome 3 duplication q21 leads to qter deletion p25 leads to pter syndrome in children of carriers of a pericentric inversion inv(3) (p25q21).
Close phenotypic similarity between two cases carrying a rec(3) dup q,inv(3) (p25q21), 12 additional infants from the same inv (3… 
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