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CDC34 gene

Known as: Cell Division Cycle 34 Homolog (S. cerevisiae) Gene, UBCH3, E2-CDC34 
This gene plays a role in protein ubiquitination.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
During ubiquitin conjugation, the thioester bond that links "donor" ubiquitin to ubiquitin-conjugating enzyme (E2) undergoes… Expand
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Highly Cited
2010
Highly Cited
2010
We describe a mechanistic model of polyubiquitination by the SCF(beta TrCP2) E3 ubiquitin (Ub) ligase using human I kappaB alpha… Expand
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Highly Cited
2009
Highly Cited
2009
microRNAs play a critically important role in a wide array of biological processes including those implicated in cancer, neuro… Expand
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Highly Cited
2005
Highly Cited
2005
Ubiquitin chains linked via lysine 48 (K48) of ubiquitin mediate recognition of ubiquitinated proteins by the proteasome. However… Expand
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Highly Cited
1998
Highly Cited
1998
In budding yeast, ubiquitination of the cyclin-dependent kinase (Cdk) inhibitor Sic1 is catalyzed by the E2 ubiquitin conjugating… Expand
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Highly Cited
1998
Highly Cited
1998
Ubiquitin-mediated proteolysis controls the abundance of many cell cycle regulatory proteins. Recent work in Saccharomyces… Expand
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Highly Cited
1998
Highly Cited
1998
In normal and transformed cells, the F-box protein p45(SKP2) is required for S phase and forms stable complexes with p19(SKP1… Expand
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Highly Cited
1997
Highly Cited
1997
Traversal from G1 to S-phase in cycling cells of budding yeast is dependent on the destruction of the S-phase cyclin/CDK… Expand
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1993
1993
In a screen designed to isolate human cDNAs that complement a yeast G2 phase checkpoint mutation (mec1), we isolated a cDNA… Expand
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Highly Cited
1988
Highly Cited
1988
Mutants in the gene CDC34 of the yeast Saccharomyces cerevisiae are defective in the transition from G1 to the S phase of the… Expand
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