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CD68 antigen, human

Known as: CD68, CD68 antigen, Macrosialin 
Macrosialin (354 aa, ~37 kDa) is encoded by the human CD68 gene. This protein may be involved in both pathogen phagocytosis and macrophage targeting.
National Institutes of Health

Related topics

Related topics

6 relations

Broader (2)

Antigens, Differentiation, MyelomonocyticCD Antigens
CD68 Ag:PrThr:Pt:Tiss:Ord:Immune stainCD68 geneCD68 wt AlleleImmune System Processes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Protective effects of triptolide on TLR4 mediated autoimmune and inflammatory response induced myocardial fibrosis in diabetic cardiomyopathy.
Highly Cited
2015
Highly Cited
2015
Microlocalization of CD68+ tumor-associated macrophages in tumor stroma correlated with poor clinical outcomes in oral squamous cell carcinoma patients
CD68 has been widely used as a pan-macrophage marker for tumor-associated macrophages (TAM) which always involve in… 
Highly Cited
2012
Highly Cited
2012
Normal breast tissue of obese women is enriched for macrophage markers and macrophage-associated gene expression
Activation of inflammatory pathways is one plausible mechanism underlying the association between obesity and increased breast… 
Highly Cited
2011
Highly Cited
2011
Investigating Vulnerable Atheroma Using Combined 18F-FDG PET/CT Angiography of Carotid Plaque with Immunohistochemical Validation
Inflammation and angiogenesis are hypothesized to be important factors contributing to plaque vulnerability, whereas… 
Highly Cited
2010
Highly Cited
2010
Characterization of monocyte/macrophage subsets in the skin and peripheral blood derived from patients with systemic sclerosis
IntroductionRecent accumulating evidence indicates a crucial involvement of macrophage lineage in the pathogenesis of systemic… 
Highly Cited
2005
Highly Cited
2005
Indeterminate cell histiocytosis: fact or fiction?
Abstract:  Indeterminate cell histiocytosis is a rare disorder, in which the predominant cells have the characteristics of both… 
Highly Cited
2003
Highly Cited
2003
Lack of a direct role for macrosialin in oxidized LDL metabolism Published, JLR Papers in Press, January 16, 2003. DOI 10.1194/jlr.M200444-JLR200
Murine macrosialin (MS), a scavenger receptor family member, is a heavily glycosylated transmembrane protein expressed… 
Highly Cited
2000
Highly Cited
2000
Localization of cyclooxygenase-2 in human sporadic colorectal adenomas.
Highly Cited
2000
Highly Cited
2000
Surface expression and rapid internalization of macrosialin (mouse CD68) on elicited mouse peritoneal macrophages
Macrosialin, the mouse homolog of human CD68, is a heavily glycosylated transmembrane protein found almost exclusively in… 
Highly Cited
1999
Highly Cited
1999
Enhanced expression of human metalloelastase (MMP-12) in cutaneous granulomas and macrophage migration.
Accumulation of inflammatory cells such as macrophages may lead to degeneration of connective tissue matrix in various skin… 
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