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CD45RO, human

Known as: CD45R0 Antigen, CD45RO Antigen, Receptor-Type Tyrosine-Protein Phosphatase C Isoform CD45RO 
CD45RO is encoded by the human PTPRC gene. This protein is involved in both tyrosine dephosphorylation and lymphocyte activity. It is an isoform of… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (1)

CD45RO Antigens
DephosphorylationEnzyme GeneEsterase GeneHydrolase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Immune Cells in Colorectal Cancer: Prognostic Relevance and Role of MSI
There is growing evidence that both local and systemic inflammatory responses play an important role in the progression of a… 
Highly Cited
2007
Highly Cited
2007
The differential regulation of Lck kinase phosphorylation sites by CD45 is critical for T cell receptor signaling responses.
Highly Cited
2002
Highly Cited
2002
Differential Association of CD45 Isoforms with CD4 and CD8 Regulates the Actions of Specific Pools of p56lck Tyrosine Kinase in T Cell Antigen Receptor Signal Transduction*
An investigation into the role of CD45 isoforms in T cell antigen receptor signal transduction was carried out by transfecting… 
Highly Cited
2000
Highly Cited
2000
Lower Proportion of CD45R0+ Cells and Deficient Interleukin-10 Production by Formula-Fed Infants, Compared With Human-Fed, Is Corrected With Supplementation of Long-Chain Polyunsaturated Fatty Acids
Background The immune consequences of adding 20:4n-6 and 22:6n-3 fatty acids to preterm infant formula are not known. Methods The… 
Highly Cited
1998
Highly Cited
1998
Differential susceptibility to activation-induced apoptosis among peripheral Th1 subsets: correlation with Bcl-2 expression and consequences for AIDS pathogenesis.
It has been proposed that HIV infection is associated with an imbalance in Th1 and Th2 subsets. Recent reports indicate that Th1… 
Highly Cited
1994
Highly Cited
1994
Expression of the G-protein--coupled receptor BLR1 defines mature, recirculating B cells and a subset of T-helper memory cells.
The G-protein-coupled receptor BLR1 related to receptors for chemokines and neuropeptides has been identified as the first… 
Highly Cited
1992
Highly Cited
1992
T cell differentiation antigens on lymphocytes in the human intestinal lamina propria.
Recently, T cell subpopulations presumably representing memory T lymphocytes have been described in vitro. Intestinal lamina… 
Highly Cited
1991
Highly Cited
1991
Germinal center T cells are distinct helper-inducer T cells.
Highly Cited
1990
Highly Cited
1990
Evidence for extrathymic changes in the T cell receptor gamma/delta repertoire
The germline repertoire of variable genes for the TCR-gamma/delta is limited. This, together with the availability of several V… 
Highly Cited
1989
Highly Cited
1989
Evidence for differential expression of CD45 isoforms by precursors for memory-dependent and independent cytotoxic responses: human CD8 memory CTLp selectively express CD45RO (UCHL1).
On the basis of differential CD45 expression, human T cells can be separated into approximately reciprocal populations. The mAb… 
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