Immune Cells in Colorectal Cancer: Prognostic Relevance and Role of MSI

@article{Deschoolmeester2011ImmuneCI,
  title={Immune Cells in Colorectal Cancer: Prognostic Relevance and Role of MSI},
  author={Vanessa Deschoolmeester and Marc F D Baay and Filip Lardon and Patrick Pauwels and Marc Peeters},
  journal={Cancer Microenvironment},
  year={2011},
  volume={4},
  pages={377-392}
}
There is growing evidence that both local and systemic inflammatory responses play an important role in the progression of a variety of solid tumors. Colorectal cancer (CRC) results from the cumulative effect of sequential genetic alterations, leading to the expression of tumor-associated antigens possibly inducing a cellular anti-tumor immune response. It is well recognized that cytotoxic lymphocytes (CTLs) constitute one of the most important effector mechanisms of anti-tumor-immunity… CONTINUE READING

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