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CD42 Complex

Known as: CD42a-d Complex, Platelet Glycoprotein Ib/V/IX Complex, CD42 Antigen 
A heterotetrameric protein complex expressed on the surface of platelets that is involved in promoting platelet adhesion to von Willebrand factor… 
National Institutes of Health

Related topics

Related topics

5 relations
GP1BA protein, humanGP1BB protein, humanPlatelet Glycoprotein IX, humanPlatelet Glycoprotein V, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Biosynthesis of platelet glycoprotein V expressed as a single subunit or in association with GPIb-IX.
Glycoprotein (GP) V is noncovalently linked to GPIbalpha, GPIbbeta and GPIX within the platelet GPIb-V-IX complex, a receptor for… 
2003
2003
A peptide isolated from αB‐crystallin is a novel and potent inhibitor of platelet aggregation via dual prevention of PAR‐1 and GPIb/V/IX
Summary.  Background: The ability of low‐molecular‐weight heat shock protein (HSP) to modulate thrombin‐induced platelet… 
Highly Cited
2002
Highly Cited
2002
GpIIb/IIIa is the main receptor for initial platelet adhesion to glass and titanium surfaces in contact with whole blood.
Platelets are the first cells to adhere to a surface in contact with blood and are capable of mediating several different… 
Review
2001
Review
2001
A New Approach to Antiplatelet Therapy: Inhibitor of GPIb/V/IX-vWF Interaction
Evidence has been presented that the interaction between von Willebrand factor (vWF) and its platelet membrane receptor, the GPIb… 
Review
2000
Review
2000
Calpain regulation of integrin alpha IIb beta 3 signaling in human platelets.
Efficient platelet adhesion and aggregation at sites of vascular injury requires the synergistic contribution of multiple… 
2000
2000
Calpain regulation of integrin a IIb 3 signaling in human platelets
Efficient platelet adhesion and aggregation at sites of vascular injury requires the synergistic contribution of multiple… 
1999
1999
A CD9, alphaIIbbeta3, integrin-associated protein, and GPIb/V/IX complex on the surface of human platelets is influenced by alphaIIbbeta3 conformational states.
A noncovalently associated complex comprising of CD9, the fibrinogen (Fg) receptor alphaIIbbeta3, integrin-associated protein… 
Highly Cited
1998
Highly Cited
1998
Naturally occurring mutations in glycoprotein Ibalpha that result in defective ligand binding and synthesis of a truncated protein.
The platelet GPIb-V-IX complex is the receptor for the initial binding of von Willebrand factor (vWF) mediating platelet adhesion… 
1997
1997
A dinucleotide deletion results in defective membrane anchoring and circulating soluble glycoprotein Ib alpha in a novel form of Bernard-Soulier syndrome.
The platelet membrane glycoprotein (GP)Ib-V-IX complex is the receptor for von Willebrand factor and is composed of four membrane… 
1997
1997
The platelet antigens CD9, CD42 and integrin alpha IIb beta IIIa can be topographically associated and transduce functionally similar signals.
Investigation of the specific effects of different mAb known to stimulate platelets (agonist mAb) is complicated by interaction… 
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