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Platelet Glycoprotein IX, human

Known as: Glycoprotein 9, Platelet Glycoprotein 9, GP-IX 
Platelet glycoprotein IX (177 aa, ~19 kDa) is encoded by the human GP9 gene. This protein plays a role in blood coagulation.
National Institutes of Health

Related topics

Related topics

12 relations
Blood PlateletsCD42 ComplexGP9 geneGP9 wt Allele

Broader (1)

Platelet Membrane Glycoprotein IX

Papers overview

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Highly Cited
2012
Highly Cited
2012
Multicolor flow cytometry for evaluation of platelet surface antigens and activation markers.
2012
2012
Platelet activation and platelet–leukocyte interaction in β-thalassemia/hemoglobin E patients with marked nucleated erythrocytosis
Patients with thalassemia, an inherited hemolytic anemia, have increased risk of hypercoagulable complications. A whole blood… 
Highly Cited
2011
Highly Cited
2011
Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIbβ and a GPIbβ/GPIX chimera.
Platelet GPIb-IX receptor complex has 3 subunits GPIbα, GPIbβ, and GPIX, which assemble with a ratio of 1:2:1. Dysfunction in… 
2011
2011
Thrombocytopenia after pig‐to‐baboon liver xenotransplantation: where do platelets go?
Ezzelarab M, Ekser B, Gridelli B, Iwase H, Ayares D, Cooper DKC. Thrombocytopenia after pig‐to‐baboon liver xenotransplantation… 
2009
2009
A large Swiss family with Bernard-Soulier syndrome
Summary Bernard-Soulier syndrome (BSS) is a rare, autosomal recessive inherited bleeding disorder associated with… 
2005
2005
Differential gene expression profile reveals deregulation of pregnancy specific β1 glycoprotein 9 early during colorectal carcinogenesis
BackgroundAPC (Adenomatous polyposis coli) plays an important role in the pathogenesis of both familial and sporadic colorectal… 
2002
2002
The cysteine knot of platelet glycoprotein Ib beta (GPIb beta) is critical for the interaction of GPIb beta with GPIX.
The glycoprotein Ib (GPIb) complex is composed of GPIb alpha covalently attached to GPIb beta and noncovalently complexed with… 
2002
2002
A Leu7Pro mutation in the signal peptide of platelet glycoprotein (GP)IX in a case of Bernard–Soulier syndrome abolishes surface expression of the GPIb–V–IX complex
Summary. This paper describes the molecular defect of the second case of Bernard–Soulier syndrome, initially reported in 1957… 
Highly Cited
2000
Highly Cited
2000
Blood platelet activation evaluated by flow cytometry: optimised methods for clinical studies
A variety of flow cytometry techniques are in use to evaluate in vivo blood platelet activation. We have in this study further… 
1993
1993
Reversibility of thrombin‐induced decrease in platelet glycoprotein Ib function
Summary. Thrombin induces a redistribution of glycoprotein (GP) Ib/GP IX complex from the platelet surface into the surface… 
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