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GP9 wt Allele

Known as: Glycoprotein IX (Platelet) Gene, Glycoprotein IX, Platelet Gene, Glycoprotein IX Platelet wt Allele 
Human GP9 wild-type allele is located in the vicinity of 3q21.3 and is approximately 7 kb in length. This allele, which encodes platelet glycoprotein… 
National Institutes of Health

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Related topics

5 relations
GP9 geneLigand BindingPlatelet ActivationPlatelet Glycoprotein IX, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Molecular basis of Bernard–Soulier syndrome in 27 patients from India
To cite this article: Sumitha E, Jayandharan GR, David S, Jacob RR, Sankari Devi G, Bargavi B, Shenbagapriya S, Nair SC, Abraham… 
Highly Cited
2006
Highly Cited
2006
Impaired megakaryocytopoiesis in type 2B von Willebrand disease with severe thrombocytopenia.
In type 2B von Willebrand disease, there is spontaneous binding of mutated von Willebrand factor (VWF) multimers to platelets… 
Highly Cited
2001
Highly Cited
2001
A Novel Monoclonal Antibody against the Extracellular Domain of GPIbβ Modulates vWF Mediated Platelet Adhesion
Summary GPIb is disulfide-linked to GPIbα to form GPIb, a platelet receptor for von Willebrand factor (vWF). GPIb is in turn non… 
1998
1998
A new variant of Bernard‐Soulier syndrome characterized by dysfunctional glycoprotein (GP) Ib and severely reduced amounts of GPIX and GPV
We describe a new variant of Bernard‐Soulier syndrome characterized by almost normal amounts of GPIb and severely reduced GPIX… 
Highly Cited
1997
Highly Cited
1997
Human endothelial cells in culture and in vivo express on their surface all four components of the glycoprotein Ib/IX/V complex.
The platelet glycoprotein Ib (GpIb) complex is composed of four polypeptides: the disulfide-linked GpIb alpha and GpIb beta and… 
1997
1997
Effect of a New Monoclonal Anti-Glycoprotein IX Antibody, KMP-9, on High Shear-Induced Platelet Aggregation
Summary Human platelet glycoprotein Ib/IX complex acts as a receptor for von Willebrand factor. It is widely accepted that… 
1997
1997
Bernard‐Soulier syndrome Karlstad: Trp 498→Stop mutation resulting in a truncated glycoprotein Ibα that contains part of the transmembranous domain
In Bernard‐Soulier syndrome, a hereditary bleeding disorder, the platelets are deficient in the glycoprotein (GP) Ib–IX–V complex… 
Highly Cited
1996
Highly Cited
1996
Analysis of the Megakaryocyte Glycoprotein IX Promoter Identifies Positive and Negative Regulatory Domains and Functional GATA and Ets Sites*
The glycoprotein (GP) Ib-V-IX multisubunit complex binds to von Willebrand factor and mediates the adhesion of platelets to the… 
Highly Cited
1995
Highly Cited
1995
Heterogenous Expression of Glycoprotein lb, IX and V in Platelets from Two Patients with Bernard-Soulier Syndrome Caused by Different Genetic Abnormalities
Summary Bernard-Soulier syndrome (BSS) is a rare inherited bleeding disorder, which is caused by deficiency or decrease of the… 
Highly Cited
1994
Highly Cited
1994
Variant Bernard-Soulier syndrome associated with a homozygous mutation in the leucine-rich domain of glycoprotein IX.
We describe a new variant of Bernard-Soulier syndrome. The patient (W.K.) showed the classic bleeding symptoms together with… 
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