FAQ

Platelet Glycoprotein V, human

Known as: Platelet Glycoprotein V, Glycoprotein 5, CD42d Antigen 
Platelet glycoprotein V (560 aa, ~61 kDa) is encoded by the human GP5 gene. This protein is involved in von Willebrand factor binding.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1965-2018
0102019652018

Related topics

Related topics

12 relations
Blood PlateletsCD42 ComplexGP5 geneGP5 wt Allele
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Broader (1)

CD42d Antigen

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Platelet Glycoprotein V, human
Plasma membrane
Blood Platelets
Platelet Activation
Megakaryocytes
Leucine-Rich Repeat

Papers overview

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Highly Cited
2007
Highly Cited
2007
Controlled shedding of platelet glycoprotein (GP)VI and GPIb-IX-V by ADAM family metalloproteinases.
BACKGROUND Platelet glycoprotein (GP)VI that binds collagen, and GPIb-IX-V that binds von Willebrand factor, initiate thrombus… (More)
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2001
2001
Platelet glycoprotein V binds to collagen and participates in platelet adhesion and aggregation.
Glycoprotein V (GPV) is a subunit of the platelet GPIb-V-IX receptor for von Willebrand factor and thrombin. GPV is cleaved from… (More)
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Highly Cited
2001
Highly Cited
2001
Platelet characteristics in patients with X-linked macrothrombocytopenia because of a novel GATA1 mutation.
A new mutation is described in the X-linked gene GATA1, resulting in macrothrombocytopenia and mild dyserythropoietic features… (More)
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2001
2001
A thrombin receptor function for platelet glycoprotein Ib-IX unmasked by cleavage of glycoprotein V.
Glycoprotein (GP) V is a major substrate cleaved by the protease thrombin during thrombin-induced platelet activation. Previous… (More)
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2001
2001
Interaction of calmodulin with the cytoplasmic domain of the platelet membrane glycoprotein Ib-IX-V complex.
Engagement of platelet membrane glycoprotein (GP) Ib-IX-V by von Willebrand factor triggers Ca(++)-dependent activation of… (More)
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1999
1999
Glycoprotein V-deficient platelets have undiminished thrombin responsiveness and Do not exhibit a Bernard-Soulier phenotype.
Adhesion of platelets to extracellular matrix via von Willebrand factor (vWF) and activation of platelets by thrombin are… (More)
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1999
1999
Increased thrombin responsiveness in platelets from mice lacking glycoprotein V.
A role for glycoprotein (GP)V in platelet function has been proposed on the basis of observations that GP V is the major thrombin… (More)
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1998
1998
Shear-dependent rolling on von Willebrand factor of mammalian cells expressing the platelet glycoprotein Ib-IX-V complex.
Mural thrombi form on exposed arterial subendothelium by a two-step process of platelet adhesion and aggregation. At high shear… (More)
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Highly Cited
1988
Highly Cited
1988
Cloning of the Alcaligenes eutrophus genes for synthesis of poly-beta-hydroxybutyric acid (PHB) and synthesis of PHB in Escherichia coli.
Eight mutants of Alcaligenes eutrophus defective in the intracellular accumulation of poly-beta-hydroxybutyric acid (PHB) were… (More)
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1983
1983
Biologic determinants of dystrophic calcification and osteocalcin deposition in glutaraldehyde-preserved porcine aortic valve leaflets implanted subcutaneously in rats.
Bioprosthetic cardiac valve calcification is a frequent complication after long-term valve replacement. In this study the authors… (More)
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