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GP1BA protein, human
Known as:
Antigen CD42b-Alpha
, Glycoprotein Ibalpha
, glycoprotein Ib (platelet), alpha polypeptide, human
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Platelet glycoprotein Ib alpha chain (652 aa, ~72 kDa) is encoded by the human GP1BA gene. This protein plays a role in von Willebrand factor binding…
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National Institutes of Health
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Related topics
Related topics
13 relations
Blood Platelets
CD42 Complex
CD42b Antigen
GP1BA gene
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Broader (1)
adhesion receptor
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Platelet GPIba Is Important for Thrombopoietin Production and Thrombopoietin-Induced Platelet Generation
Miao Xu
,
Li Ma
,
+5 authors
H. Ni
2015
Corpus ID: 78321394
Background: Platelets are generated from megakaryocytes in the bone marrow and play a key role in hemostasis. GPIba is the major…
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2014
2014
Novel genetic abnormalities in Bernard-Soulier syndrome in India
S. Ali
,
K. Ghosh
,
S. Shetty
Annals of Hematology
2014
Corpus ID: 1447159
Bernard-Soulier syndrome (BSS) is a severe inherited bleeding disorder due to defects in GPIb/IX/V, a platelet receptor that…
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2010
2010
Transmembrane and Trans-subunit Regulation of Ectodomain Shedding of Platelet Glycoprotein Ibα*
X. Mo
,
N. Nguyen
,
+6 authors
Renhao Li
Journal of Biological Chemistry
2010
Corpus ID: 22714727
Ectodomain shedding of transmembrane proteins may be regulated by their cytoplasmic domains. To date, the effecting cytoplasmic…
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2008
2008
Lack of association between aspirin responsiveness and seven candidate gene haplotypes in patients with symptomatic vascular disease
T. Kunicki
,
Shirley A. Williams
,
+4 authors
P. Rothwell
Thrombosis and Haemostasis
2008
Corpus ID: 21689646
Summary We studied the effect of prophylactic aspirin (ASA) ingestion on platelet function in 463 patients with stroke, transient…
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2007
2007
Glycoprotein Ibα Polymorphism T145M, Elevated Lipoprotein-Associated Phospholipase A2, and Hypertriglyceridemia Predict Risk for Recurrent Coronary Events in Diabetic Postinfarction Patients
J. Corsetti
,
D. Ryan
,
A. Moss
,
D. Rainwater
,
W. Zareba
,
C. Sparks
Diabetes
2007
Corpus ID: 39667285
To explore altered platelet function in recurrent coronary event risk among diabetic postinfarction patients, we investigated a…
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2004
2004
A 13 base pair deletion in the GPIbβ gene in a second unrelated Bernard–Soulier family due to slipped mispairing between direct repeats
C. Strassel
,
M. Alessi
,
I. Juhan-vague
,
J. Cazenave
,
F. Lanza
Journal of Thrombosis and Haemostasis
2004
Corpus ID: 46340563
Bernard–Soulier syndrome (BSS) is a congenital recessive disorder characterized by a prolonged bleeding time…
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Highly Cited
2003
Highly Cited
2003
Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha.
R. Celikel
,
R. McClintock
,
+4 authors
Z. Ruggeri
Science
2003
Corpus ID: 12498877
Thrombin bound to platelets contributes to stop bleeding and, in pathological conditions, may cause vascular thrombosis. We have…
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Highly Cited
2000
Highly Cited
2000
The Asp272–Glu282 Region of Platelet Glycoprotein Ibα Interacts with the Heparin-binding Site of α-Thrombin and Protects the Enzyme from the Heparin-catalyzed Inhibition by Antithrombin III*
R. De Cristofaro
,
E. De Candia
,
S. Rutella
,
J. Weitz
Journal of Biological Chemistry
2000
Corpus ID: 55845390
Platelet glycoprotein Ib (GpIb) mediates interaction with both von Willebrand factor and thrombin. Thrombin binds to GpIb via its…
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1998
1998
Characteristics of the Interaction between Thrombin Exosite1 and the Sequence 269-297 of Platelet Glycoprotein Ibα
M. Bouton
,
C. Thurieau
,
M. Guillin
,
M. Jandrot-Perrus
Thrombosis and Haemostasis
1998
Corpus ID: 13853138
Summary The interaction between GPIb and thrombin promotes platelet activation elicited via the hydrolysis of the thrombin…
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1998
1998
New alleles of the platelet glycoprotein Ibalpha gene.
J. Corral
,
R. González-Conejero
,
M. Lozano
,
J. Rivera
,
V. Vicente
British Journal of Haematology
1998
Corpus ID: 35650540
Platelet membrane glycoprotein Ibalpha (GP Ibalpha) bears two molecular polymorphisms which are in linkage disequilibrium: the C…
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