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CD22 antigen

Known as: Sialic Acid Binding Ig like Lectin 2, CD22 Glycoprotein, Antigen, CD22 
A lectin and cell adhesion molecule found in B-LYMPHOCYTES. It interacts with SIALIC ACIDS and mediates signaling from B-CELL ANTIGEN RECEPTORS.
National Institutes of Health

Papers overview

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2013
2013
The regulatory functions of Siglecs (sialic acid binding immunoglobulin-like lectins) in the immune system provide opportunities… Expand
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2013
2013
  • Daphne Y. Ma, M. Suthar, Shinji Kasahara, Michael Gale, Edward A. Clark
  • Journal of Virology
  • 2013
  • Corpus ID: 25992649
ABSTRACT West Nile virus (WNV) is a RNA virus of the family Flaviviridae and the leading cause of mosquito-borne encephalitis in… Expand
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2012
2012
CD22 (Siglec‐2) is a B‐cell membrane‐bound lectin that recognizes glycan ligands containing α2,6‐linked sialic acid (α2,6Sia) and… Expand
Highly Cited
2006
Highly Cited
2006
CD22 (Siglec-2) is a key regulator of B cell signaling whose function is modulated by interaction with extracellular glycan… Expand
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Highly Cited
2003
Highly Cited
2003
The Siglec family of receptors mediates cell surface interactions through recognition of sialylated glycoconjugates. The crystal… Expand
Highly Cited
2000
Highly Cited
2000
  • Els C. M. Brinkman-Van der Linden, Eric R. Sjoberg, Lekh Raj Juneja, P. Crocker, Nissi Varki, A. Varki
  • The Journal of Biological Chemistry
  • 2000
  • Corpus ID: 23214152
The common sialic acids of mammalian cells areN-acetylneuraminic acid (Neu5Ac) andN-glycolylneuraminic acid (Neu5Gc). Humans are… Expand
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Highly Cited
1998
Highly Cited
1998
Mice in which the Lyn, Cd22, or Shp-1 gene has been disrupted have hyperactive B cells and autoantibodies. We find that in the… Expand
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Highly Cited
1993
Highly Cited
1993
CD22 is a B lineage-restricted member of the Ig superfamily that serves as an adhesion receptor expressed by mature B lymphocytes… Expand
1993
1993
Background. Cell adhesion molecules (CAM) may determine the patterns of growth and dissemination of lymphoproliferative disorders… Expand
Highly Cited
1991
Highly Cited
1991
We have cloned a full-length cDNA for the B cell membrane protein CD22, which is referred to as B lymphocyte cell adhesion… Expand
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