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CD22 antigen

Known as: Sialic Acid Binding Ig like Lectin 2, CD22 Glycoprotein, Antigen, CD22 
A lectin and cell adhesion molecule found in B-LYMPHOCYTES. It interacts with SIALIC ACIDS and mediates signaling from B-CELL ANTIGEN RECEPTORS.
National Institutes of Health

Papers overview

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2013
2013
West Nile virus (WNV) is a RNA virus of the family Flaviviridae and the leading cause of mosquito-borne encephalitis in the… Expand
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2013
2013
The regulatory functions of Siglecs (sialic acid binding immunoglobulin-like lectins) in the immune system provide opportunities… Expand
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2012
2012
CD22 (Siglec-2) is a B-cell membrane-bound lectin that recognizes glycan ligands containing α2,6-linked sialic acid (α2,6Sia) and… Expand
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Highly Cited
2006
Highly Cited
2006
CD22 (Siglec-2) is a key regulator of B cell signaling whose function is modulated by interaction with extracellular glycan… Expand
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2003
2003
The Siglec family of receptors mediates cell surface interactions through recognition of sialylated glycoconjugates. The crystal… Expand
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Highly Cited
2000
Highly Cited
2000
The common sialic acids of mammalian cells are N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc). Humans… Expand
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Highly Cited
1998
Highly Cited
1998
Mice in which the Lyn, Cd22, or Shp-1 gene has been disrupted have hyperactive B cells and autoantibodies. We find that in the… Expand
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Highly Cited
1993
Highly Cited
1993
CD22 is a B lineage-restricted member of the Ig superfamily that serves as an adhesion receptor expressed by mature B lymphocytes… Expand
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1993
1993
BACKGROUND Cell adhesion molecules (CAM) may determine the patterns of growth and dissemination of lymphoproliferative disorders… Expand
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Highly Cited
1991
Highly Cited
1991
We have cloned a full-length cDNA for the B cell membrane protein CD22, which is referred to as B lymphocyte cell adhesion… Expand
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