CD22 antigen

Known as: Sialic Acid Binding Ig like Lectin 2, CD22 Glycoprotein, Antigen, CD22 
A lectin and cell adhesion molecule found in B-LYMPHOCYTES. It interacts with SIALIC ACIDS and mediates signaling from B-CELL ANTIGEN RECEPTORS.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1977-2018
02419772018

Papers overview

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Highly Cited
2008
Highly Cited
2008
We have targeted CD22 as a novel tumor-associated Ag for recognition by human CTL genetically modified to express chimeric TCR… (More)
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2003
2003
The Siglec family of receptors mediates cell surface interactions through recognition of sialylated glycoconjugates. The crystal… (More)
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1995
1995
The B-cell receptor CD22 binds sialic acid linked alpha-2-6 to terminal galactose residues on N-linked oligosaccharides… (More)
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1994
1994
Using molecular modeling technology, we have recently identified two positions in conserved framework regions of antibody Fv… (More)
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1994
1994
Disulfide-stabilized Fvs (dsFv) are recombinant Fv fragments of antibodies in which the inherently unstable VH-VL heterodimer is… (More)
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1991
1991
The genes encoding the heavy- and light-chain Fv regions of the monoclonal murine antibody B3, which recognizes a carbohydrate… (More)
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1991
1991
B3 is a monoclonal antibody that reacts with a carbohydrate epitope present on a variety of proteins located on the surface of… (More)
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1987
1987
A detailed immunohistologic and cytogenetic analysis of 12 cases of intermediate lymphocytic lymphoma was performed. The… (More)
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1987
1987
Two monoclonal antibodies (To15 and 4KB128) specific for the B cell-associated CD22 antigen (135,000 mol wt) are described. On… (More)
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1985
1985
The phenotypic expression of Hodgkin's and Reed-Sternberg (H-RS) cells was determined by analysis with a panel of monoclonal… (More)
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