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CD22 gene
Known as:
CD22
, SIALIC ACID-BINDING IMMUNOGLOBULIN-LIKE LECTIN 2
, CD22 molecule
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This gene is involved in mediating the adhesion between B cells and is a molecular marker for B-cell precursor acute lymphocytic leukemia.
National Institutes of Health
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Related topics
Related topics
5 relations
CD22 Expressing Cell Count
CD22 antigen
CD22 protein, human
Cell Adhesion
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Preclinical Development of Bivalent Chimeric Antigen Receptors Targeting Both CD19 and CD22
Haiying Qin
,
S. Ramakrishna
,
+8 authors
T. Fry
Molecular therapy oncolytics
2018
Corpus ID: 56595290
Highly Cited
2006
Highly Cited
2006
Isolation of anti-CD22 Fv with high affinity by Fv display on human cells.
Mitchell Ho
,
S. Nagata
,
I. Pastan
Proceedings of the National Academy of Sciences…
2006
Corpus ID: 25433063
In vitro antibody affinity maturation has generally been achieved by display of mouse or human antibodies on the surface of…
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Highly Cited
2005
Highly Cited
2005
Homomultimeric complexes of CD22 in B cells revealed by protein-glycan cross-linking
Shoufa Han
,
B. E. Collins
,
P. Bengtson
,
J. Paulson
Nature chemical biology
2005
Corpus ID: 28991013
CD22 is a negative regulator of B-cell receptor signaling, an activity mediated by recruitment of SH2 domain–containing…
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Highly Cited
1999
Highly Cited
1999
Identification of the gene variations in human CD22
Y. Hatta
,
N. Tsuchiya
,
M. Matsushita
,
M. Shiota
,
K. Hagiwara
,
K. Tokunaga
Immunogenetics
1999
Corpus ID: 22947237
Abstract CD22, a member of the immunoglobulin superfamily, is a B-cell transmembrane glycoprotein that acts as an accessory…
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Review
1997
Review
1997
CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling.
T. Tedder
,
J. Tuscano
,
S. Sato
,
J. Kehrl
Annual review of immunology
1997
Corpus ID: 8046679
The development of B lymphocytes is a highly regulated process that depends in part on lineage-specific cell surface molecules…
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Highly Cited
1996
Highly Cited
1996
CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice.
S. Sato
,
A. Miller
,
+4 authors
T. Tedder
Immunity
1996
Corpus ID: 6605276
1996
1996
A Single N-linked Glycosylation Site Is Implicated in the Regulation of Ligand Recognition by the I-type Lectins CD22 and CD33*
D. Sgroi
,
A. Nocks
,
I. Stamenkovic
The Journal of Biological Chemistry
1996
Corpus ID: 9534238
CD22 is an immunoglobulin superfamily B lymphocyte-specific adhesion receptor and a member of the recently identified I-type…
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Highly Cited
1993
Highly Cited
1993
The same epitope on CD22 of B lymphocytes mediates the adhesion of erythrocytes, T and B lymphocytes, neutrophils, and monocytes.
P. Engel
,
Y. Nojima
,
+4 authors
T. Tedder
Journal of immunology
1993
Corpus ID: 19997720
CD22 is a B lineage-restricted member of the Ig superfamily that serves as an adhesion receptor expressed by mature B lymphocytes…
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Highly Cited
1993
Highly Cited
1993
Association of CD22 with the B cell antigen receptor
C. Peaker
,
M. Neuberger
European journal of immunology
1993
Corpus ID: 23285160
The antigen receptor on B lymphocytes is composed of membrane immunoglobulin sheathed by an α/β heterodimer. This structure is in…
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Highly Cited
1992
Highly Cited
1992
Identification and characterization of the murine homologue of CD22, a B lymphocyte-restricted adhesion molecule.
R. Torres
,
C. Law
,
+4 authors
E. Clark
Journal of immunology
1992
Corpus ID: 35751592
The human B lymphocyte-specific Ag, CD22, is a cell adhesion molecule expressed on the surface during a narrow window of B cell…
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