Skip to search formSkip to main contentSkip to account menu

CD22 gene

Known as: CD22, SIALIC ACID-BINDING IMMUNOGLOBULIN-LIKE LECTIN 2, CD22 molecule 
This gene is involved in mediating the adhesion between B cells and is a molecular marker for B-cell precursor acute lymphocytic leukemia.
National Institutes of Health

Related topics

Related topics

5 relations
CD22 Expressing Cell CountCD22 antigenCD22 protein, humanCell Adhesion

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Preclinical Development of Bivalent Chimeric Antigen Receptors Targeting Both CD19 and CD22
Highly Cited
2006
Highly Cited
2006
Isolation of anti-CD22 Fv with high affinity by Fv display on human cells.
In vitro antibody affinity maturation has generally been achieved by display of mouse or human antibodies on the surface of… 
Highly Cited
2005
Highly Cited
2005
Homomultimeric complexes of CD22 in B cells revealed by protein-glycan cross-linking
CD22 is a negative regulator of B-cell receptor signaling, an activity mediated by recruitment of SH2 domain–containing… 
Highly Cited
1999
Highly Cited
1999
Identification of the gene variations in human CD22
Abstract CD22, a member of the immunoglobulin superfamily, is a B-cell transmembrane glycoprotein that acts as an accessory… 
Review
1997
Review
1997
CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling.
The development of B lymphocytes is a highly regulated process that depends in part on lineage-specific cell surface molecules… 
Highly Cited
1996
Highly Cited
1996
CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice.
1996
1996
A Single N-linked Glycosylation Site Is Implicated in the Regulation of Ligand Recognition by the I-type Lectins CD22 and CD33*
CD22 is an immunoglobulin superfamily B lymphocyte-specific adhesion receptor and a member of the recently identified I-type… 
Highly Cited
1993
Highly Cited
1993
The same epitope on CD22 of B lymphocytes mediates the adhesion of erythrocytes, T and B lymphocytes, neutrophils, and monocytes.
CD22 is a B lineage-restricted member of the Ig superfamily that serves as an adhesion receptor expressed by mature B lymphocytes… 
Highly Cited
1993
Highly Cited
1993
Association of CD22 with the B cell antigen receptor
The antigen receptor on B lymphocytes is composed of membrane immunoglobulin sheathed by an α/β heterodimer. This structure is in… 
Highly Cited
1992
Highly Cited
1992
Identification and characterization of the murine homologue of CD22, a B lymphocyte-restricted adhesion molecule.
The human B lymphocyte-specific Ag, CD22, is a cell adhesion molecule expressed on the surface during a narrow window of B cell… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License