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CA9 wt Allele

Known as: Carbonic Anhydrase IX wt Allele, G250, CA9 
Human CA9 wild-type allele is located in the vicinity of 9p13.3 and is approximately 7 kb in length. This allele, which encodes carbonic anhydrase 9… 
National Institutes of Health

Papers overview

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2017
2017
Clinically relevant HIF-1α-dependent metabolic reprogramming in oropharyngeal squamous cell carcinomas includes coordinated activation of CAIX and the miR-210/ISCU signaling axis, but not MCT1 and…
Metabolic reprogramming is a very heterogeneous phenomenon in cancer. It mostly consists on increased glycolysis, lactic acid… 
2012
2012
Predictive factors for response to treatment in patients with advanced renal cell carcinoma
SummaryIntroduction The analysis of predictive factors of response may aid in predicting which patients with advanced renal cell… 
2011
2011
5-aminolevulinic acid induce apoptosis via NF-κB/JNK pathway in human oral cancer Ca9-22 cells.
BACKGROUND 5-aminolevulinic acid-based photodynamic therapy (5-ALA-PDT) is being used to treat oral pre-cancerous and cancerous… 
2010
2010
A New Peptide Ligand for Targeting Human Carbonic Anhydrase IX, Identified through the Phage Display Technology
Carbonic anhydrase IX (CAIX) is a transmembrane enzyme found to be overexpressed in various tumors and associated with tumor… 
2008
2008
Hypoxia inducible factor (HIF1α and HIF2α) and carbonic anhydrase 9 (CA9) expression and response of head-neck cancer to hypofractionated and accelerated radiotherapy
Purpose: Tumor hypoxia and low intrinsic radiosensitivity may counteract the efficacy of standard radiotherapy for locally… 
2008
2008
A tumor targeted gene vector modified with G250 monoclonal antibody for gene therapy.
Highly Cited
2006
Highly Cited
2006
Comparison between pimonidazole binding, oxygen electrode measurements, and expression of endogenous hypoxia markers in cancer of the uterine cervix
Although tumor hypoxia has been associated with a more aggressive phenotype and lower cure rate, there is no consensus as to the… 
2003
2003
Interferons can upregulate the expression of the tumor associated antigen G250-MN/CA IX, a potential target for (radio)immunotherapy of renal cell carcinoma.
BACKGROUND Interleukin-2 (IL-2) and interferon-alpha (IFN-alpha) can induce therapeutic responses in a minority (5-25%) of… 
2001
2001
The expression of G250/mn/CA9 antigen by flow cytometry: its possible implication for detection of micrometastatic renal cancer cells.
Monoclonal antibody (mAb) G250 is a well characterized and specific mAb to renal cell carcinoma (RCC). The gene G250 was recently… 
1999
1999
In vivo and in vitro characterizations of three 99mTc-labeled monoclonal antibody G250 preparations.
UNLABELLED In previous clinical studies, excellent visualization of tumor lesions has been observed with 131I-labeled monoclonal… 
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