clobazam

Known as: Clobazamum, 1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepine, clobazam [Chemical/Ingredient]

A 1,5-benzodiazepine and partial gamma-aminobutyric acid (GABA) receptor agonist, with anxiolytic, sedative, and anticonvulsant activities. Clobazam…

National Institutes of Health

Papers overview

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2014

Background and purpose: Febrile seizure is a seizure associated with fever without any evidence of intracranial infection or…

1989

Clobazam was used as an added treatment in 28 patients with intractable epilepsies: 26 subjects had associated handicaps. A good…

1989

Clobazam, a 1-5 benzodiazepine with anxiolytic properties, was evaluated in the treatment of patients with DSM-III panic disorder…

1984

The objective of this investigation was to determine whether the effects of muscimol on benzodiazepine receptor binding relate to…

1980

Electron-capture GLC was utilized for simultaneous quantitation of clobazam, a 1,5-benzodiazepine derivative, and its active…

1979

1 The detracting psychomotor effects of diazepam (5 mg three times daily) and clobazam (an investigational 1,5-benzodiazepine…

1979

1 Clobazam has been assayed in human serum using a radioreceptor technique. 2 The assay is simple and sufficiently sensitive for…

1979

1 Forty-four clinically anxious patients entered a comparative double-blind trial of clobazam 20 mg, clobazam 30 mg and…

1979

1 Extensive toxicological investigations of clobazam are summarized. 2 LD50 values after oral administration ranged from 100 mg…

1978

Two dose levels of clobazam, a benzodiazepine derivative, were compared to placebo for their effects upon psychomotor performance…