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Bone Morphogenetic Protein 3

Known as: Bone Morphogenetic Protein 3 [Chemical/Ingredient], Osteogenin 
A bone morphogenetic protein that is found at high concentrations in a purified osteoinductive protein fraction from BONE. Bone morphogenetic protein… Expand
National Institutes of Health

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Related topics

11 relations
BMP3 geneIn BloodProcess of secretionagonists
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BMP3 protein, human

Broader (1)

Proteins

Papers overview

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Review
2001
Review
2001
BMP3: To Be or Not To Be a BMP
Background: Bone morphogenetic proteins (BMPs) are osteogenic but also have diverse functions during development. BMP3 is a major… Expand
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Highly Cited
1994
Highly Cited
1994
Developing human lung and kidney are major sites for synthesis of bone morphogenetic protein-3 (osteogenin).
Bone morphogenetic protein-3 (BMP-3; osteogenin) is a member of the transforming growth factor-beta superfamily. We used human… Expand
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Highly Cited
1992
Highly Cited
1992
Osteogenin, a bone morphogenetic protein, adsorbed on porous hydroxyapatite substrata, induces rapid bone differentiation in calvarial defects of adult primates.
Osteogenin, a bone morphogenetic protein, in conjunction with insoluble collagenous bone matrix initiates local endochondral bone… Expand
Highly Cited
1992
Highly Cited
1992
The critical role of geometry of porous hydroxyapatite delivery system in induction of bone by osteogenin, a bone morphogenetic protein.
The collagenous extracellular matrix of bone obtained after dissociative extraction with 4 M guanidine-HCl is an optimal… Expand
Highly Cited
1991
Highly Cited
1991
Tissue transformation into bone in vivo. A potential practical application.
The transformation of mesenchymal tissue, such as muscle, into cartilage and bone can be induced by the recently purified… Expand
Highly Cited
1991
Highly Cited
1991
Histologic comparison of regeneration in human intrabony defects when osteogenin is combined with demineralized freeze-dried bone allograft and with purified bovine collagen.
A bone-inductive protein, osteogenin, has been isolated from long bones of humans and offers promise as a grafting material… Expand
Highly Cited
1990
Highly Cited
1990
Interaction of osteogenin, a heparin binding bone morphogenetic protein, with type IV collagen.
Osteogenin, an extracellular matrix component of bone, is a heparin binding differentiation factor that initiates endochondral… Expand
Highly Cited
1989
Highly Cited
1989
Purification and partial amino acid sequence of osteogenin, a protein initiating bone differentiation.
Osteogenin was purified from bovine bone matrix and its activity monitored by an in vivo bone induction assay. The purification… Expand
Highly Cited
1989
Highly Cited
1989
Stimulation of the expression of osteogenic and chondrogenic phenotypes in vitro by osteogenin.
Osteogenin was recently purified and the amino acid sequences of tryptic peptides were determined. Osteogenin in conjunction with… Expand
Highly Cited
1988
Highly Cited
1988
Dose-dependence of and threshold for optimal bone induction by collagenous bone matrix and osteogenin-enriched fraction.
Subcutaneous implantation of demineralized collagenous bone matrix results in local induction of new bone formation. The dose… Expand
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