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Bleomycin

Known as: Bleomicina, Bleomycins, Bleomycin Antibiotic 
A basic glycopeptide antineoplastic antibiotic isolated from Streptomyces verticillus. Bleomycin antibiotics form complexes with iron that react with… 
National Institutes of Health

Related topics

Related topics

47 relations

Narrower (21)

BCD protocolBLEDTABLEO-cellBleomycin A2
BOMP protocolBleomycin SulfateBleomycin/Methotrexate/VinblastineBleomycin/Prednisone/Vincristine regimen (BOP)

Broader (1)

Glycopeptides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
miR-29 inhibits bleomycin-induced pulmonary fibrosis in mice.
Loss of microRNA-29 (miR-29) is known to be a mechanism of transforming growth factor-β (TGF-β)-mediated pulmonary fibrosis, but… 
Highly Cited
2010
Highly Cited
2010
Repetitive intratracheal bleomycin models several features of idiopathic pulmonary fibrosis.
Single-dose intratracheal bleomycin has been instrumental for understanding fibrotic lung remodeling, but fails to recapitulate… 
Highly Cited
2009
Highly Cited
2009
Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis.
RATIONALE Lung fibroblasts are key mediators of fibrosis resulting in accumulation of excessive interstitial collagen and… 
Highly Cited
2009
Highly Cited
2009
Human umbilical cord mesenchymal stem cells reduce fibrosis of bleomycin-induced lung injury.
Acute respiratory distress syndrome is characterized by loss of lung tissue as a result of inflammation and fibrosis. Augmenting… 
Review
2005
Review
2005
Mechanisms of bleomycin-induced lung damage
Bleomycins are a family of compounds produced byStreptomyces verticillis. They have potent tumour killing properties which have… 
Review
2005
Review
2005
Bleomycin pulmonary toxicity has a negative impact on the outcome of patients with Hodgkin's lymphoma.
PURPOSE Bleomycin pulmonary toxicity (BPT) has been well described in Hodgkin's lymphoma (HL) patients treated with bleomycin… 
Highly Cited
2000
Highly Cited
2000
Bleomycin-induced pulmonary fibrosis in fibrinogen-null mice.
Mice deleted for the plasminogen activator inhibitor-1 (PAI-1) gene are relatively protected from developing pulmonary fibrosis… 
Highly Cited
1993
Highly Cited
1993
Effect of antibody to transforming growth factor beta on bleomycin induced accumulation of lung collagen in mice.
BACKGROUND--Increased production of transforming growth factor beta (TGF-beta) seems to have an important role in the… 
Highly Cited
1989
Highly Cited
1989
Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis
The role of TNF-alpha/cachectin in the pneumopathy elicited by bleomycin has been investigated. After a single intratracheal… 
Highly Cited
1974
Highly Cited
1974
The pathogenesis of bleomycin-induced pulmonary fibrosis in mice.
Administration of 0.5 mg bleomycin to mice twice weekly for 4 weeks induced pulmonary fibrosis. The initial site of injury was… 
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