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Bleomycin

Known as: Bleomicina, Bleomycins, Bleomycin Antibiotic 
A basic glycopeptide antineoplastic antibiotic isolated from Streptomyces verticillus. Bleomycin antibiotics form complexes with iron that react with… 
National Institutes of Health

Related topics

Related topics

47 relations

Narrower (21)

BCD protocolBLEDTABLEO-cellBleomycin A2
BOMP protocolBleomycin SulfateBleomycin/Methotrexate/VinblastineBleomycin/Prednisone/Vincristine regimen (BOP)

Broader (1)

Glycopeptides

Papers overview

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1985
1985
Control of release rate of bleomycin from polylactic acid microspheres by additives.
Polylactic acid (PLA) microspheres containing bleomycin were prepared by a solventevaporation process. The release rate of… 
Highly Cited
1981
Highly Cited
1981
An active intermediate formed in the reaction of bleomycin-Fe(II) complex with oxygen.
The base-release activity of oxygen adduct of bleomycin-Fe(II) complex [BLM-Fe(II)] from DNA decreased with a half-life of 5.2… 
1980
1980
Assessment of bleomycin lung toxicity using angiotensin-converting enzyme in pulmonary lavage.
Activity of the dipeptidyl hydrolase angiotensin-converting enzyme has been observed to be altered by treatment with bleomycin… 
Highly Cited
1980
Highly Cited
1980
Effect of bestatin on mouse immune system and experimental murine tumors.
Effect of bestatin on the establishment of delayed-type hypersensitivity (DTH) to sheep red blood cells (SRBC) and oxazolone was… 
1978
1978
Fundamental and clinical studies on new bleomycin analogs.
  • A. MatsudaOsamu Yoshioka S. Nagai
  • Recent results in cancer research. Fortschritte…
  • 1978
  • Corpus ID: 38242987
In the last 15 years, there has been great progress in the study of antitumor antibiotics. Professor Umezawa in his early study… 
Highly Cited
1975
Highly Cited
1975
Binding of bleomycin to DNA in bleomycin-sensitive and -resistant rat ascites hepatoma cells.
The 14C activity of [14C]bleomycin bound to DNA in bleomycin-sensitive rat ascites hepatoma cells (AH-66) was 8.7 times higher… 
1975
1975
Chemical and biologic properties of isolated radiolabeled bleomycin preparations.
Cobalt-57-bleomycin is a diagnostically useful radiopharmaceutical, but little is known about the nature of its individual… 
1975
1975
Reversible interstitial pneumonitis associated with low dose bleomycin.
A patient with nodular histiocytic lymphoma was treated with bleomycin; she later developed interstitial pneumonitis documented… 
1973
1973
Breakage of a DNA-protein complex induced by bleomycin and their repair in cultured mouse fibroblasts.
The effect of bleomycin on DNA strand breakage and its repair in cultured mouse fibroblast strain L·P3 (a substrain of L929) was… 
1968
1968
The distribution of 3H-bleomycin in mouse tissue.
A bleomycin mixture which contained A2 as the main component and B2 as the second component was tritiated. The 3H-bleomycin thus…