Beta-cell Function Measurement

Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic traits, we performed meta-analyses… Expand

OBJECTIVE To determine the efficacy and safety of liraglutide (a glucagon-like peptide-1 receptor agonist) when added to… Expand

BACKGROUND The expression of interleukin-1-receptor antagonist is reduced in pancreatic islets of patients with type 2 diabetes… Expand

BACKGROUND The efficacy of thiazolidinediones, as compared with other oral glucose-lowering medications, in maintaining long-term… Expand

Islet transplantation can restore endogenous beta-cell function to subjects with type 1 diabetes. Sixty-five patients received an… Expand

The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes have been… Expand

BACKGROUND Childhood obesity, epidemic in the United States, has been accompanied by an increase in the prevalence of type 2… Expand

Type 2 diabetes frequently results from progressive failure of pancreatic beta-cell function in the presence of chronic insulin… Expand

BACKGROUND Glucagon-like peptide 1 (GLP-1) has been proposed as a treatment for type 2 diabetes. We have investigated the long… Expand

To determine the relationship between insulin sensitivity and β-cell function, we quantified the insulin sensitivity index using… Expand