Beta-cell Function Measurement

Known as: BCEFNCTN, Beta-cell Function 
The determination of the beta cell function (insulin production and secretion) in a biological specimen.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
BACKGROUND The immunopathogenesis of type 1 diabetes mellitus is associated with T-lymphocyte autoimmunity. However, there is… (More)
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Highly Cited
2008
Highly Cited
2008
Decreases in both beta-cell function and number can contribute to insulin deficiency in type 2 diabetes. Here, we quantified the… (More)
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Review
2007
Review
2007
There is a progressive deterioration in beta-cell function and mass in type 2 diabetics. It was found that islet function was… (More)
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Highly Cited
2005
Highly Cited
2005
The nature of the progressive beta-cell failure occurring as normal glucose tolerant (NGT) individuals progress to type 2… (More)
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Highly Cited
2004
Highly Cited
2004
The underlying cause of type 1 diabetes, loss of beta-cell function, has become the therapeutic target for a number of… (More)
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Review
2003
Review
2003
The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes have been… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Glucagon-like peptide 1 (GLP-1) has been proposed as a treatment for type 2 diabetes. We have investigated the long… (More)
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Highly Cited
2002
Highly Cited
2002
Type 2 diabetes frequently results from progressive failure of pancreatic beta-cell function in the presence of chronic insulin… (More)
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Highly Cited
1999
Highly Cited
1999
Oxidative stress is produced under diabetic conditions and possibly causes various forms of tissue damage in patients with… (More)
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Highly Cited
1993
Highly Cited
1993
To determine the relationship between insulin sensitivity and beta-cell function, we quantified the insulin sensitivity index… (More)
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