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BW 723C86

Known as: BW-723C86, BW723C86 
National Institutes of Health

Papers overview

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2019
2019
Anxiety-induced hyperalgesia in female rats is mediated by cholecystokinin 2 receptor in rostral ventromedial medulla and spinal 5-hydroxytryptamine 2B receptor
Background Preoperative anxiety is associated with postoperative hyperalgesia; however, few studies have investigated the… 
2018
2018
Inhibition of 5‐Hydroxytryptamine Receptor 2B Reduced Vascular Restenosis and Mitigated the β‐Arrestin2–Mammalian Target of Rapamycin/p70S6K Pathway
Background As a monoamine neurotransmitter, 5‐hydroxytryptamine (5‐HT) or serotonin modulates mood, appetite, and sleep. Besides… 
2016
2016
A Novel Role of Serotonin Receptor 2B Agonist as an Anti-Melanogenesis Agent
BW723C86, a serotonin receptor 2B agonist, has been investigated as a potential therapeutic for various conditions such as… 
2016
2016
Serotonin 5-HT2B Receptor-Stimulated DNA Synthesis and Proliferation Are Mediated by Autocrine Secretion of Transforming Growth Factor-α in Primary Cultures of Adult Rat Hepatocytes.
The mechanism of serotonin 5-HT2 receptor subtype-stimulated DNA synthesis and proliferation was investigated in primary cultures… 
2016
2016
Facilitation of serotonin-induced contraction of rat mesenteric artery by ketamine
Ketamine is an anesthetic with hypertensive effects, which make it useful for patients at risk of shock. However, previous ex… 
2008
2008
5HT2 receptor activation facilitates P2X receptor mediated excitatory neurotransmission to cardiac vagal neurons in the nucleus ambiguus
2007
2007
Possible involvement of endogenous 5-HT in aggravation of cerulein-induced acute pancreatitis in mice.
The aim of the present study was to elucidate the pathogenic role of endogenous 5-HT in pancreatitis. Injections of cerulein at… 
2006
2006
Human trabecular meshwork cells express functional serotonin-2A (5HT2A) receptors: role in IOP reduction.
PURPOSE To apply a multidisciplinary approach to the identification and pharmacological characterization of the serotonin (5HT… 
2005
2005
Implication of 5-HT2 receptor subtypes in the mechanism of action of antidepressants in the four plates test
RationaleThe selective serotonin reuptake inhibitors (SSRIs) and the serotonin and noradrenaline reuptake inhibitors (SNRIs… 
2001
2001
Investigations into Migraine Pathogenesis: Time Course for Effects of m-CPP, BW723C86 or Glyceryl Trinitrate on Appearance of Fos-Like Immunoreactivity in Rat Trigeminal Nucleus Caudalis (TNC)
Clinical and preclinical studies suggest that 5-HT and nitric oxide (NO) mobilization within the trigeminovascular system is… 
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