BTNL2 gene

Known as: BTNL2, BUTYROPHILIN-LIKE PROTEIN 2, BTL II 
This gene plays a role in the regulation of T-cell proliferation.
National Institutes of Health

Related topics

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4 relations
BTNL3 geneBTNL8 geneBTNL9 geneButyrophilin-Like Protein 2, human

Papers overview

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2013
2013
Germline missense variants in the BTNL2 gene are associated with prostate cancer susceptibility.
BACKGROUND Rare, inherited mutations account for 5% to 10% of all prostate cancer cases. However, to date, few causative… (More)
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2013
2013
Exome sequencing identifies novel rheumatoid arthritis-susceptible variants in the BTNL2
The butyrophilin-like protein 2 gene (BTNL2) within the class III region of the major histocompatibility complex genomic region… (More)
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2012
2012
BTNL2 gene polymorphism associations with susceptibility and phenotype expression in sarcoidosis.
A functional polymorphism within butyrophilin-like 2 (BTNL2) gene has been described as a potential risk factor for sarcoidosis… (More)
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2011
2011
The BTNL2 A allele variant is frequent in Danish patients with sarcoidosis.
BACKGROUND The butyrophilin-like 2 (BTNL2) gene is located on chromosome 6p21.3 close to the HLA-class II genes. An association… (More)
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Highly Cited
2009
Highly Cited
2009
Forty-Three Loci Associated with Plasma Lipoprotein Size, Concentration, and Cholesterol Content in Genome-Wide Analysis
While conventional LDL-C, HDL-C, and triglyceride measurements reflect aggregate properties of plasma lipoprotein fractions, NMR… (More)
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Highly Cited
2008
Highly Cited
2008
Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility
Inflammatory bowel disease (IBD) typically manifests as either ulcerative colitis (UC) or Crohn's disease (CD). Systematic… (More)
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Highly Cited
2007
Highly Cited
2007
BTNL2, a butyrophilin/B7-like molecule, is a negative costimulatory molecule modulated in intestinal inflammation.
Butyrophilin-like 2 (BTNL2) is a butyrophilin family member with homology to the B7 costimulatory molecules, polymorphisms of… (More)
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Highly Cited
2006
Highly Cited
2006
BTNL2, a butyrophilin-like molecule that functions to inhibit T cell activation.
B7 family members regulate T cell activation and tolerance. Although butyrophilin proteins share sequence homology with the B7… (More)
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Highly Cited
2005
Highly Cited
2005
Sarcoidosis is associated with a truncating splice site mutation in BTNL2
Sarcoidosis is a polygenic immune disorder with predominant manifestation in the lung. Genome-wide linkage analysis previously… (More)
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2005
2005
Analysis of a functional BTNL2 polymorphism in type 1 diabetes, rheumatoid arthritis, and systemic lupus erythematosus.
The aim of this study was to test whether the functional variant rs2076530 of the BTNL2 gene confers susceptibility to the… (More)
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