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BTNL2 gene

Known as: BTNL2, BUTYROPHILIN-LIKE PROTEIN 2, BTL II 
This gene plays a role in the regulation of T-cell proliferation.
National Institutes of Health

Related topics

Related topics

4 relations
BTNL3 geneBTNL8 geneBTNL9 geneButyrophilin-Like Protein 2, human

Papers overview

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2011
2011
An Investigation of Genome-Wide Studies Reported Susceptibility Loci for Ulcerative Colitis Shows Limited Replication in North Indians
Genome-Wide Association studies (GWAS) of both Crohn's Disease (CD) and Ulcerative Colitis (UC) have unearthed over 40 risk… Expand
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Highly Cited
2009
Highly Cited
2009
Forty-Three Loci Associated with Plasma Lipoprotein Size, Concentration, and Cholesterol Content in Genome-Wide Analysis
While conventional LDL-C, HDL-C, and triglyceride measurements reflect aggregate properties of plasma lipoprotein fractions, NMR… Expand
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Highly Cited
2009
Highly Cited
2009
Ulcerative colitis loci on chromosomes 1p36 and 12q15 identified by genome-wide association study
Ulcerative colitis is a chronic inflammatory disease of the colon that presents as diarrhea and gastrointestinal bleeding. We… Expand
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Highly Cited
2008
Highly Cited
2008
Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility
Inflammatory bowel disease (IBD) typically manifests as either ulcerative colitis (UC) or Crohn's disease (CD). Systematic… Expand
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Highly Cited
2007
Highly Cited
2007
BTNL2, a Butyrophilin/B7-Like Molecule, Is a Negative Costimulatory Molecule Modulated in Intestinal Inflammation
Butyrophilin-like 2 (BTNL2) is a butyrophilin family member with homology to the B7 costimulatory molecules, polymorphisms of… Expand
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Highly Cited
2006
Highly Cited
2006
BTNL2, a Butyrophilin-Like Molecule That Functions to Inhibit T Cell Activation1
B7 family members regulate T cell activation and tolerance. Although butyrophilin proteins share sequence homology with the B7… Expand
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Highly Cited
2006
Highly Cited
2006
BTNL2 gene variant and sarcoidosis
Sarcoidosis is an inflammatory granulomatous disorder that primarily affects the lungs and lymph nodes. Other organs such as the… Expand
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Highly Cited
2005
Highly Cited
2005
Sarcoidosis is associated with a truncating splice site mutation in BTNL2
Sarcoidosis is a polygenic immune disorder with predominant manifestation in the lung. Genome-wide linkage analysis previously… Expand
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Highly Cited
2005
Highly Cited
2005
The BTNL2 gene and sarcoidosis susceptibility in African Americans and Whites.
The BTNL2 gene is a member of the B7 receptor family that probably functions as a T-cell costimulatory molecule. It resides in… Expand
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Highly Cited
2000
Highly Cited
2000
BTL-II : a polymorphic locus with homology to the butyrophilin gene family, located at the border of the major histocompatibility complex class II and class III regions in human and mouse
Abstract Comparison of human and mouse genomic sequence at the border of the major histocompatibility complex (MHC) class II and… Expand
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