BNIP3 gene

Known as: BCL2/ADENOVIRUS E1B 19-KD PROTEIN-INTERACTING PROTEIN 3, BCL2/adenovirus E1B 19kDa interacting protein 3, BNIP3 
This gene plays a role in the stimulation of both apoptosis and autophagy.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
While hypoxia-inducible factor (HIF) is a major actor in the cell survival response to hypoxia, HIF also is associated with cell… (More)
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Highly Cited
2008
Highly Cited
2008
Macroautophagy (called autophagy hereafter) is a catabolic process activated by various types of stress, most notably by nutrient… (More)
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Highly Cited
2007
Highly Cited
2007
Hypoxia and nutrient deprivation are environmental stresses governing the survival and adaptation of tumor cells in vivo. We have… (More)
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Highly Cited
2007
Highly Cited
2007
Following myocardial infarction, nonischemic myocyte death results in infarct expansion, myocardial loss, and ventricular… (More)
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Highly Cited
2005
Highly Cited
2005
Arsenic trioxide (As2O3) has shown considerable efficacy in treating hematological malignancies with induction of programmed cell… (More)
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Highly Cited
2004
Highly Cited
2004
The sphingolipid ceramide has been recognized as an important second messenger implicated in regulating diverse signaling… (More)
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Highly Cited
2002
Highly Cited
2002
Coronary artery disease leads to injury and loss of myocardial tissue by deprivation of blood flow (ischemia) and is a major… (More)
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Highly Cited
2001
Highly Cited
2001
Solid tumors contain regions of hypoxia, a physiological stress that can activate cell death pathways and, thus, result in the… (More)
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Highly Cited
2001
Highly Cited
2001
It has been shown that oxygen deprivation results in apoptotic cell death, and that hypoxia inducible factor 1 (HIF1) and the… (More)
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Highly Cited
2000
Highly Cited
2000
Many apoptotic signaling pathways are directed to mitochondria, where they initiate the release of apoptogenic proteins and open… (More)
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