BID protein

Known as: BH3 Interacting Domain Death Agonist Protein [Chemical/Ingredient], BID, BH3 Interacting Domain Death Agonist Protein 
BH3-interacting domain death agonist (195 aa, ~22 kDa) is encoded by the human BID gene. This protein plays a role in the promotion of apoptosis.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Although the proteins BAX and BAK are required for initiation of apoptosis at the mitochondria, how BAX and BAK are activated… (More)
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Highly Cited
2006
Highly Cited
2006
We show that the antiapoptotic proteins BCL-2, BCL-XL, MCL-1, BFL-1, and BCL-w each bear a unique pattern of interaction with a… (More)
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Highly Cited
2006
Highly Cited
2006
BAX is a multidomain proapoptotic BCL-2 family protein that resides in the cytosol until activated by an incompletely understood… (More)
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Highly Cited
2002
Highly Cited
2002
The role of the p53 protein (encoded by TP53) in tumour suppression relies partly on the ability of p53 to regulate the… (More)
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Highly Cited
2000
Highly Cited
2000
Many apoptotic molecules relocate subcellularly in cells undergoing apoptosis. The pro-apoptotic protein BID underwent… (More)
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Highly Cited
2000
Highly Cited
2000
TNFR1/Fas engagement results in the cleavage of cytosolic BID to truncated tBID, which translocates to mitochondria… (More)
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Highly Cited
1999
Highly Cited
1999
"BH3 domain only" members of the BCL-2 family including the pro-apoptotic molecule BID represent candidates to connect with… (More)
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Highly Cited
1999
Highly Cited
1999
Members of the BCL2 family of proteins are key regulators of programmed cell death, acting either as apoptotic agonists or… (More)
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Highly Cited
1998
Highly Cited
1998
We report here that BID, a BH3 domain-containing proapoptotic Bcl2 family member, is a specific proximal substrate of Casp8 in… (More)
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Highly Cited
1996
Highly Cited
1996
The BCL-2 family of proteins consists of both antagonists (e.g., BCL-2) and agonists (e.g., BAX) that regulate apoptosis and… (More)
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