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BID protein

Known as: BH3 Interacting Domain Death Agonist Protein [Chemical/Ingredient], BID, BH3 Interacting Domain Death Agonist Protein 
BH3-interacting domain death agonist (195 aa, ~22 kDa) is encoded by the human BID gene. This protein plays a role in the promotion of apoptosis.
National Institutes of Health

Related topics

Related topics

23 relations
Alzheimer's Disease Pathway KEGGApoptosisApoptosis PromoterBH3 Domain

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tBid Protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Phase I study of CAL-101, an isoform-selective inhibitor of phosphatidylinositol 3-kinase P110d, in patients with previously treated chronic lymphocytic leukemia.
6631 Background: The class I phosphatidylinositol 3-kinases (PI3Ks) regulate cellular functions relevant to oncogenesis… 
Highly Cited
2009
Highly Cited
2009
A first-in-human phase I study to evaluate the pan-PI3K inhibitor GDC-0941 administered QD or BID in patients with advanced solid tumors.
3501 Background: The PI3K-PTEN-AKT signaling pathway is deregulated in a wide variety of cancers. GDC-0941 is a potent and… 
Highly Cited
2008
Highly Cited
2008
Pharmacokinetics of gabapentin after a single day and at steady state following the administration of gastric-retentive- extended-release and immediate-release tablets: a randomized, open-label…
Highly Cited
2008
Highly Cited
2008
Sphingosine-1-phosphate mediates transcriptional regulation of key targets associated with survival, proliferation, and pluripotency in human embryonic stem cells.
Human embryonic stem cells (hESCs) replicate in vitro by the process of self-renewal, whilst maintaining their pluripotency… 
Highly Cited
2007
Highly Cited
2007
Nebulized arformoterol in patients with COPD: a 12-week, multicenter, randomized, double-blind, double-dummy, placebo- and active-controlled trial.
Highly Cited
2002
Highly Cited
2002
Ectopic expression of Bcl-2 and Bcl-xL inhibits apoptosis induced by TNF-related apoptosis-inducing ligand (TRAIL) through suppression of caspases-8, 7, and 3 and BID cleavage in human acute…
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is one of the latest members of the TNF superfamily known… 
Highly Cited
2001
Highly Cited
2001
Tumor necrosis factor alpha induces BID cleavage and bypasses antiapoptotic signals in prostate cancer LNCaP cells.
Survival of cancer cells in response to therapy, immune response, or metastasis depends on interactions between pro- and… 
Highly Cited
1998
Highly Cited
1998
Characterization of t(2;5) reciprocal transcripts and genomic breakpoints in CD30+ cutaneous lymphoproliferations.
NPM-ALK chimeric transcripts, encoded by the t(2;5), lead to an aberrant expression of ALK by CD30+ systemic lymphomas. To… 
Highly Cited
1995
Highly Cited
1995
Short-Course Ciproflox Treatment of Acute Uncomplicated Urinary Tract Infection in Women: The Minimum Effective Dose
Background: Three studies were undertaken to determine the minimum effective dosing regimen of ciprofloxacin for the treatment of… 
1992
1992
Concomitant boost technique using accelerated superfractionated radiation therapy for advanced squamous cell carcinoma of the head and neck
Of 142 patients irradiated for American Joint Committee on Cancer Stage III or IV head and neck carcinoma, 100 patients were… 
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