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Aged Long-Evans rats were screened for spatial memory deficits using the Morris water maze task. Rats found to have impaired… Expand Hippocampal-dependent learning and memory deficits have been well documented in aging rodents. The results of several recent… Expand Alzheimer's disease (AD) is a neurodegenerative disease characterized by cognitive impairment and personality changes. The… Expand Changes in hippocampal electroencephalogram (EEG) have been suggested to be closely associated with spatial learning ability… Expand Elevated levels of circulating estrogen in female rats result in increased spine and synapse density and parallel increases in… Expand The 5th International Geneva/Springfield Symposium on Advances in Alzheimer Therapy focused on new therapeutic approaches for the… Expand The present study examined the role of muscarinic receptors in the discriminative stimulus properties of clozapine. One group of… Expand Mild to moderate traumatic brain injury (TBI) is associated with enduring impairments of cognitive function in both humans and… Expand Aged memory-impaired (AI) and unimpaired (AU) 24–25-month-old Long- Evans rats were used to investigate the integrity of various… Expand The present study was designed to characterize the receptor selectivity profile of the novel muscarinic M2 receptor antagonist… Expand