FAQ

BETA-N-ACETYLHEXOSAMINIDASE

Known as: beta N Acetyl hexosaminidase, N-Acetyl-beta-D-hexosaminidase, beta N Acetylhexosaminidases 
A hexosaminidase specific for non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. It acts on GLUCOSIDES; GALACTOSIDES; and… (More)

Topic mentions per year

Topic mentions per year

1964-2017
05019642017

Related topics

Related topics

17 relations
Gangliosidoses, GM2In BloodLiverLysosomes
(More)

Broader (1)

Hexosaminidases

Narrower (1)

peptide O-linked N-acetylglucosamine-beta-N-acetylglucosaminidase

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
BETA-N-ACETYLHEXOSAMINIDASE
physiological aspects
Liver
Lysosomes
chemical synthesis
Tay-Sachs Disease

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease
Intracranial transplantation of neural stem cells (NSCs) delayed disease onset, preserved motor function, reduced pathology and… (More)
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2006
2006
Characterization of a beta-N-acetylhexosaminidase and a beta-N-acetylglucosaminidase/beta-glucosidase from Cellulomonas fimi.
The gram-positive soil bacterium Cellulomonas fimi is shown to produce at least two intracellular beta-N-acetylglucosaminidases… (More)
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Highly Cited
2004
Highly Cited
2004
Lysosomal glycosphingolipid recognition by NKT cells.
NKT cells represent a distinct lineage of T cells that coexpress a conserved alphabeta T cell receptor (TCR) and natural killer… (More)
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Highly Cited
2003
Highly Cited
2003
Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcepsilonRI or…
Two novel stem cell factor (SCF) dependent human mast cell lines, designated LAD 1 and 2, were established from bone marrow… (More)
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Highly Cited
2001
Highly Cited
2001
Rab27a Is Required for Regulated Secretion in Cytotoxic T Lymphocytes
Rab27a activity is affected in several mouse models of human disease including Griscelli (ashen mice) and Hermansky-Pudlak… (More)
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Highly Cited
2001
Highly Cited
2001
The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein.
Sortilin belongs to a growing family of multiligand type-1 receptors with homology to the yeast receptor Vps10p. Based on… (More)
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Highly Cited
2000
Highly Cited
2000
Microglial activation precedes acute neurodegeneration in Sandhoff disease and is suppressed by bone marrow transplantation.
Sandhoff disease is a lysosomal storage disorder characterized by the absence of beta-hexosaminidase and storage of G(M2… (More)
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Highly Cited
1998
Highly Cited
1998
Loss of endosomal/lysosomal membrane impermeability is an early event in amyloid Abeta1-42 pathogenesis.
Previous studies have implicated the failure to degrade aggregated Abeta1-42 in late endosomes or secondary lysosomes as a… (More)
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Highly Cited
1984
Highly Cited
1984
Measurement of cell numbers by means of the endogenous enzyme hexosaminidase. Applications to detection of lymphokines and cell surface antigens.
By using a chromogenic substrate for an ubiquitous lysosomal enzyme, hexosaminidase to estimate cell numbers, a sensitive and… (More)
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Highly Cited
1969
Highly Cited
1969
Tay-Sachs disease: generalized absence of a beta-D-N-acetylhexosaminidase component.
Two hexosaminidase components, separable by starch-gel electrophoresis and possessing both beta-D-N-acetylglucosaminidase and… (More)
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