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BETA-N-ACETYLHEXOSAMINIDASE

Known as: beta N Acetyl hexosaminidase, N-Acetyl-beta-D-hexosaminidase, beta N Acetylhexosaminidases 
A hexosaminidase specific for non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. It acts on GLUCOSIDES; GALACTOSIDES; and… Expand
National Institutes of Health

Related topics

Related topics

16 relations
Gangliosidoses, GM2Hexosaminidase A fr SerIn BloodLiver
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Broader (1)

Hexosaminidases

Narrower (1)

peptide O-linked N-acetylglucosamine-beta-N-acetylglucosaminidase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Lysosomal Glycosphingolipid Recognition by NKT Cells
NKT cells represent a distinct lineage of T cells that coexpress a conserved αβ T cell receptor (TCR) and natural killer (NK… Expand
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Highly Cited
2003
Highly Cited
2003
Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcepsilonRI or…
Two novel stem cell factor (SCF) dependent human mast cell lines, designated LAD 1 and 2, were established from bone marrow… Expand
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Highly Cited
2001
Highly Cited
2001
The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein.
Sortilin belongs to a growing family of multiligand type-1 receptors with homology to the yeast receptor Vps10p. Based on… Expand
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Highly Cited
2000
Highly Cited
2000
Microglial activation precedes acute neurodegeneration in Sandhoff disease and is suppressed by bone marrow transplantation.
Sandhoff disease is a lysosomal storage disorder characterized by the absence of beta-hexosaminidase and storage of G(M2… Expand
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Highly Cited
1998
Highly Cited
1998
Loss of endosomal/lysosomal membrane impermeability is an early event in amyloid Abeta1-42 pathogenesis.
Previous studies have implicated the failure to degrade aggregated Abeta1-42 in late endosomes or secondary lysosomes as a… Expand
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Highly Cited
1997
Highly Cited
1997
Lysosomes Behave as Ca2+-regulated Exocytic Vesicles in Fibroblasts and Epithelial Cells
Lysosomes are considered to be a terminal degradative compartment of the endocytic pathway, into which transport is mostly… Expand
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Highly Cited
1984
Highly Cited
1984
Interleukin 3: A differentiation and growth factor for the mouse mast cell that contains chondroitin sulfate E proteoglycan.
Mouse mast cells were differentiated and grown by culturing bone marrow cells in medium containing 2 X 10(-10) M purified… Expand
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Highly Cited
1982
Highly Cited
1982
Prostaglandin D2 generation after activation of rat and human mast cells with anti-IgE.
Anti-IgE-dependent activation of rat and human mast cells resulted in the preferential generation of the cyclooxygenase products… Expand
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Highly Cited
1981
Highly Cited
1981
Acid hydrolases and tryptase from secretory granules of dispersed human lung mast cells.
beta-Hexosaminidase, beta-glucuronidase, arylsulfatase, and tryptase were each released along with histamine from dispersed… Expand
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Highly Cited
1969
Highly Cited
1969
Tay-Sachs Disease: Generalized Absence of a Beta-D-N-Acetylhexosaminidase Component
Two hexosaminidase components, separable by starch-gel electrophoresis and possessing both β-D-N-acetylglucosaminidase and β-D-N… Expand
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