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BETA-N-ACETYLHEXOSAMINIDASE

Known as: beta N Acetyl hexosaminidase, N-Acetyl-beta-D-hexosaminidase, beta N Acetylhexosaminidases 
A hexosaminidase specific for non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. It acts on GLUCOSIDES; GALACTOSIDES; and… 
National Institutes of Health

Related topics

Related topics

16 relations
Gangliosidoses, GM2Hexosaminidase A fr SerIn BloodLiver

Broader (1)

Hexosaminidases

Narrower (1)

peptide O-linked N-acetylglucosamine-beta-N-acetylglucosaminidase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
The Drosophila fused lobes Gene Encodes an N-Acetylglucosaminidase Involved in N-Glycan Processing*
Most processed, e.g. fucosylated, N-glycans on insect glycoproteins terminate in mannose, yet the relevant modifying enzymes… 
Highly Cited
2002
Highly Cited
2002
Structural requirements of flavonoids for inhibition of antigen-Induced degranulation, TNF-alpha and IL-4 production from RBL-2H3 cells.
Highly Cited
2000
Highly Cited
2000
Dependence of mast cell IgE-mediated cytokine production on nuclear factor-kappaB activity.
BACKGROUND The transcription factor nuclear factor-kappaB (NF-kappaB) has been implicated in the regulation of a number of… 
Highly Cited
2000
Highly Cited
2000
Molecular mechanisms of platelet exocytosis: role of SNAP-23 and syntaxin 2 and 4 in lysosome release.
On stimulation by strong agonists, platelets release the contents of 3 storage compartments in 2 apparent waves of exocytosis… 
Highly Cited
1999
Highly Cited
1999
SLP-76 deficiency impairs signaling via the high-affinity IgE receptor in mast cells.
SLP-76 is an adapter protein expressed in T cells and myeloid cells that is a substrate for ZAP-70 and Syk. SLP-76-deficient mice… 
Highly Cited
1997
Highly Cited
1997
Apoptotic cell death in mouse models of GM2 gangliosidosis and observations on human Tay-Sachs and Sandhoff diseases.
Tay-Sachs and Sandhoff diseases are autosomal recessive neurodegenerative diseases resulting from the inability to catabolize GM2… 
Highly Cited
1988
Highly Cited
1988
The major defect in Ashkenazi Jews with Tay-Sachs disease is an insertion in the gene for the alpha-chain of beta-hexosaminidase.
Highly Cited
1983
Highly Cited
1983
The role of intermediate vesicles in the adsorptive endocytosis and transport of ligand to lysosomes by human fibroblasts
Recent work from several laboratories has suggested the participation of intermediate structures in the delivery of adsorbed… 
Highly Cited
1975
Highly Cited
1975
Defective lysosomal enzyme secretion in kidneys of Chediak-Higashi (beige) mice
The beige mouse is an animal model for the human Chediak-Higashi syndrome, a disease characterized by giant lysosomes in most… 
Highly Cited
1968
Highly Cited
1968
Deficient hexosaminidase activity in an exceptional case of Tay-Sachs disease with additional storage of kidney globoside in visceral organs.
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