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Hexosaminidases

Known as: Hexosaminidase, Hexosaminidases [Chemical/Ingredient] 
Enzymes that catalyze the hydrolysis of N-acylhexosamine residues in N-acylhexosamides. Hexosaminidases also act on GLUCOSIDES; GALACTOSIDES; and… 
National Institutes of Health

Related topics

Related topics

16 relations

Narrower (7)

1,4-beta-chitobiosidaseBETA-N-ACETYLHEXOSAMINIDASEGalactosaminidasesGlucosaminidases
GangliosidosesIn BloodProcess of secretionantagonists & inhibitors

Broader (1)

Glycoside Hydrolases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1991
1991
Effects of metal elements on beta-hexosaminidase release from rat basophilic leukemia cells (RBL-2H3).
Immediate allergy is caused by a chemical mediator released from basophile and mast cells via cell degranulation due to reaction… 
1983
1983
Activating proteins for ganglioside GM2 degradation by beta-hexosaminidase isoenzymes in tissue extracts from different species.
The existence of activator proteins that stimulate hydrolysis of ganglioside GM2 by beta-hexosaminidase was demonstrated in… 
Highly Cited
1980
Highly Cited
1980
The subunit and polypeptide structure of hexosaminidases from human placenta.
Previous reports have indicated that the hexosaminidases (HEX) are tetrameric enzymes composed of either two dimers of β chains… 
1979
1979
Selective hepatic uptake of human beta-hexosaminidase A by a specific glycoprotein recognition system on sinusoidal cells.
Intravenously administered (125)I-labeled human beta-hexosaminidase A (beta-N-acetylglucosaminidase; 2-acetamido-2-deoxy-beta-D… 
1978
1978
Biochemical and immunochemical characterization of hexosaminidase P.
Hexasaminidase P, the main isozyme of hexosaminidase in pregnancy serum, was isolated and purified 600--700-fold by a two-step… 
Highly Cited
1977
Highly Cited
1977
Immunochemical analysis of the N-acetyl hexosaminidases in human-mouse hybrids made using a double selective system.
A human-mouse hybrid, DUR 4 (Solomon et al., 1976), containing a human X/15 translocation chromosome and also chromosome 5, among… 
1977
1977
Immunochemical and biochemical investigation of hexosaminidase S.
Hexosaminidase S (HEX S), the residual isozyme found in tissues and body fluids of children with the O variant of GM2… 
1977
1977
Purification of two hexosaminidases from human kidney.
Hexosaminidase forms A and B were isolated from human kidney in a homogeneous state as demonstrated by electrophoretic and… 
1976
1976
Studies on complementation of beta hexosaminidase deficiency in human GM2 gangliosidosis.
Complementation of beta hexosaminidase A (hex A) deficiency was obtained by Sendai virus-mediated somatic cell hybridization of… 
1976
1976
The subunits of human hexosaminidase A.
Previous studies of the subunit structure of hexosaminidase gave ambiguous results, but suggested that the enzyme was composed of… 
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