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BCL11A gene

Known as: EVI9, MOUSE, HOMOLOG OF, EVI9, B-Cell CLL/Lymphoma 11A (Zinc Finger Protein) Gene 
This gene is involved in both the modulation of cell shape and lymphopoiesis.
National Institutes of Health

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B-Cell Lymphoma/Leukemia 11ABCL11A protein, humanHematopoiesisRegulation of Cell Shape

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BCL11A wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Enucleation and Beta-Globin Expression in Induced Red Blood Cells: A Platform to Model Sickle Cell Anemia
Human induced pluripotent stem cells (hiPSCs) hold tremendous promise for disease modeling and the development of novel… 
2016
2016
Genetic Variants at BCL11A and HBS1L-MYB loci Influence Hb F Levels in Chinese Zhuang β-Thalassemia Intermedia Patients
Abstract Increased Hb F levels can ameliorate the symptoms of β-thalassemia (β-thal). Due to the genetic heterogenicity of β-thal… 
2015
2015
Single-cell analysis reveals key roles for Bcl11a in regulating stem cell fate decisions
Cell-cycle fluctuations drive significant transcriptomic heterogeneity in murine hematopoietic stem cells. Additionally, deletion… 
Review
2014
Review
2014
Fetal Hemoglobin Induction to Treat b-Hemoglobinopathies : From Bench to Bedside
The developmental regulation of the γto β-globin switch has motivated research efforts to establish therapeutic modalities for… 
2013
2013
RED CELLS , IRON , AND ERYTHROPOIESIS LIN 28 B-mediated expression of fetal hemoglobin and production of fetal-like erythrocytes from adult human erythroblasts ex vivo
• LIN28B regulates HbF expression in erythroblasts that are cultured from umbilical cord and adult human blood. • LIN28B… 
2012
2012
Novel therapeutic agents for HbF induction: a new era for treatment of β thalassemia?
Fetal globin is endogenous, normally integrated in hematopoietic stem cells in all humans, and available for reactivation… 
2012
2012
Hematopoietic SIN Lentiviral Micro RNA-Mediated Silencing of BCL11A: Pre-Clinical Evidence for a Sickle Cell Disease Gene-Therapy Trial
Abstract 753 Sickle cell disease (SCD) is caused by a mutation in the β-globin protein, leading to the polymerization of… 
2011
2011
Functional Evaluation of HbF-Associated Region of BCL11A Locus
Abstract 2148 The severity of the major β-globin disorders, sickle cell disease and β-thalassemia, is modified by the residual… 
2007
2007
Characterization of CTIP 1 Interaction with HP 1 By
Approved: Mark Leid / Dorina Avram COUP-TF interacting protein 1 (CTIP1) is a novel C2H2 zinc finger protein that mediates… 
2001
2001
Characterization of CTIP1 interaction with HP1
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