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BAG4 wt Allele

Known as: BAG-4, BCL2-Associated Athanogene 4 wt Allele, SODD 
Human BAG4 wild-type allele is located in the vicinity of 8p12 and is approximately 37 kb in length. This allele, which encodes BAG family molecular… 
National Institutes of Health

Related topics

Related topics

8 relations
8p11.21Homo sapiensNegative Regulation of ApoptosisReceptor Signaling

Broader (1)

BAG4 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Expression and Clinical Role of Antiapoptotic Proteins of the Bag, Heat Shock, and Bcl-2 Families in Effusions, Primary Tumors, and Solid Metastases in Ovarian Carcinoma
Cancer progression is associated with reduced apoptosis and increased proliferation. We hypothesized that upregulation of the Bag… 
2007
2007
BAG-4/SODD and Associated Antiapoptotic Proteins Are Linked to Aggressiveness of Epithelial Ovarian Cancer
Purpose: We hypothesized that elevated expression in ovarian cancer of the BAG family of prosurvival proteins and associated… 
Highly Cited
2005
Highly Cited
2005
Dual function of membrane-bound heat shock protein 70 (Hsp70), Bag-4, and Hsp40: protection against radiation-induced effects and target structure for natural killer cells
CX+/CX− and Colo+/Colo− tumor sublines with stable heat shock protein 70 (Hsp70) high and low membrane expression were generated… 
Highly Cited
2003
Highly Cited
2003
Role of SODD in Regulation of Tumor Necrosis Factor Responses
ABSTRACT Signaling from tumor necrosis factor receptor type 1 (TNFR1) can elicit potent inflammatory and cytotoxic responses that… 
2003
2003
Expression of silencer of death domains and death-receptor-3 in normal human kidney and in rejecting renal transplants.
Highly Cited
2001
Highly Cited
2001
Isolation of Bcl-2 binding proteins that exhibit homology with BAG-1 and suppressor of death domains protein.
The Bcl-2 oncoprotein is a potent inhibitor of apoptosis and is overexpressed in a variety of different malignancies. Bcl-2… 
Highly Cited
2001
Highly Cited
2001
Samui, a novel cold-inducible gene, encoding a protein with a BAG domain similar to silencer of death domains (SODD/BAG-4), isolated from Bombyx diapause eggs.
Cellular responses to cold-acclimation have not yet been studied in depth. To explore this field, we focussed on insect diapause… 
2000
2000
Enhanced expression of Silencer of death domains (SODD/BAG-4) in pancreatic cancer.
Pancreatic cancers are resistant to TNF-alpha-mediated apoptosis. Silencer of death domains (SODD) binds to TNF-alpha receptor… 
Highly Cited
1999
Highly Cited
1999
An Evolutionarily Conserved Family of Hsp70/Hsc70 Molecular Chaperone Regulators*
Heat Shock Protein 70 kDa (Hsp70) family molecular chaperones play critical roles in protein folding and trafficking in all… 
Highly Cited
1999
Highly Cited
1999
Prevention of constitutive TNF receptor 1 signaling by silencer of death domains.
Tumor necrosis factor receptor type 1 (TNF-R1) contains a cytoplasmic death domain that is required for the signaling of TNF… 
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