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A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer.
- J. Neoptolemos, D. Stocken, +13 authors M. Büchler
- The New England journal of medicine
- 18 March 2004
Adjuvant chemotherapy has a significant survival benefit in patients with resected pancreatic cancer, whereas adjuvant chemoradiotherapy has a deleterious effect on survival. Expand
Delayed gastric emptying (DGE) after pancreatic surgery: a suggested definition by the International Study Group of Pancreatic Surgery (ISGPS).
The proposed definition, which includes a clinical grading of DGE, should allow objective and accurate comparison of the results of future clinical trials and will facilitate the objective evaluation of novel interventions and surgical modalities in the field of pancreatic surgery. Expand
Recalling Superior Mesenteric Artery Syndrome
Superior mesenteric artery syndrome is clearly defined and frequently associated with a wide range of predisposing conditions and surgical procedures; clinicians have to consider this syndrome in such a setting. Expand
IAP Guidelines for the Surgical Management of Acute Pancreatitis
During 2002 the International Association of Pancreatology developed evidenced-based guidelines on the surgical management of acute pancreatitis, which should form the basis for audit studies in order to determine the quality of patient care delivery. Expand
Posthepatectomy liver failure: a definition and grading by the International Study Group of Liver Surgery (ISGLS).
A definition and grading of severity of posthepatectomy liver failure is proposed, which can be used in future studies to allow objective and accurate comparisons of operative interventions in the field of hepatic surgery. Expand
Adjuvant chemotherapy with fluorouracil plus folinic acid vs gemcitabine following pancreatic cancer resection: a randomized controlled trial.
Compared with the use of fluorouracil plus folinic acid, gemcitabine did not result in improved overall survival in patients with completely resected pancreatic cancer. Expand
Definition and grading of anastomotic leakage following anterior resection of the rectum: a proposal by the International Study Group of Rectal Cancer.
The proposed definition and clinical grading of anastomotic leakage is applicable easily in the setting of clinical studies and should be applied in future reports to facilitate valid comparison of the results of different studies. Expand
Bile leakage after hepatobiliary and pancreatic surgery: a definition and grading of severity by the International Study Group of Liver Surgery.
A uniform definition and severity grading of bile leakage is proposed to enable a standardized comparison of the results of different clinical trials and may facilitate an objective evaluation of diagnostic and therapeutic modalities in the field of hepatobiliary and pancreatic operative therapy. Expand
Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial
The adjuvant combination of gem citabine and capecitabine should be the new standard of care following resection for pancreatic ductal adenocarcinoma. Expand
Postpancreatectomy hemorrhage (PPH): an International Study Group of Pancreatic Surgery (ISGPS) definition.
An objective, universally accepted definition and clinical grading of PPH is important for the appropriate management and use of interventions in PPH and would allow comparisons of results from future clinical trials. Expand