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Azurophilic granules

Known as: Azurophilic Granule 
A cytoplasmic granule found in the myelocyte lineage that can be stained with azure dyes.
National Institutes of Health

Related topics

Related topics

3 relations
Azurophilic Granule MeasurementLeukocytesLysosomes

Papers overview

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2010
2010
Stimulation of human neutrophils with sera containing HLA Class I alloantibody causes preferential degranulation of azurophilic granules and secretory vesicles
Background and Objectives  The activation of neutrophils by human leukocyte antigen (HLA) Class I alloantibody is thought to be… 
2009
2009
Signalling mechanisms for Toll‐like receptor‐activated neutrophil exocytosis: key roles for interleukin‐1‐receptor‐associated kinase‐4 and phosphatidylinositol 3‐kinase but not Toll/IL‐1 receptor…
Lipopolysaccharide (LPS) stimulates exocytosis in neutrophils. The signalling molecules involved in the regulation of this… 
Highly Cited
2006
Highly Cited
2006
Combinatorial SNARE Complexes Modulate the Secretion of Cytoplasmic Granules in Human Neutrophils1
Mobilization of human neutrophil granules is critical for the innate immune response against infection and for the outburst of… 
Review
1999
Review
1999
Quality control in the endoplasmic reticulum: lessons from hereditary myeloperoxidase deficiency.
Highly Cited
1993
Highly Cited
1993
Regulation of CD11b/CD18 expression in human neutrophils by phospholipase A2.
Recent evidence suggests that phospholipase A2 (PLA2)-derived lipid mediators may regulate a number of neutrophil responses… 
Highly Cited
1988
Highly Cited
1988
Phospholipase A2 activity in resting and activated human neutrophils. Substrate specificity, pH dependence, and subcellular localization.
We have studied the phospholipase A2 activity in fractionated human neutrophils, employing labeled phosphatidylinositol… 
1987
1987
Protein kinase C inhibition by sphingoid long-chain bases: effects on secretion in human neutrophils.
1986
1986
Isolation of human neutrophil plasma membranes employing neutrophil cytoplasts and changes in the cell-surface proteins upon cell activation.
1986
1986
Phospholipid metabolism in human neutrophil subfractions.
Highly Cited
1983
Highly Cited
1983
Conversion of leukotriene D4 to leukotriene E4 by a dipeptidase released from the specific granule of human polymorphonuclear leucocytes.
Leukotriene D4 (LTD4), the most active spasmogenic leukotriene constituent of the slow reacting substance of anaphylaxis was… 
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