Azurophilic granules

Background: Protein paucimannosylation is considered an important invertebrate- and plant-specific glycoepitope. Results… Expand

Human neutrophils represent the predominant leucocyte in circulation and the first responder to infection. Concurrent with… Expand

Neutrophils rely on exocytosis to mobilize receptors and adhesion molecules and to release microbicidal factors. This process… Expand

BACKGROUND New experimental approaches to the study of the neutrophil phagosome and bacterial killing prompted a reassessment of… Expand

Neutrophil granules contain secretory molecules that contribute to the implementation of all neutrophil functions. The molecular… Expand

We recently reported that the human pathogen Streptococcus pyogenes of the M1 serotype survives and replicates intracellularly… Expand

Mobilization of human neutrophil granules is critical for the innate immune response against infection and for the outburst of… Expand

Human neutrophils have an important role in host defense against microbial infection. At different stages of an infectious… Expand

A 5-week-old male infant presented with severe bacterial infections and poor wound healing, suggesting a neutrophil defect… Expand

We have developed an alternative method to study the degranulation in electropermeabilized human neutrophils by measuring the up… Expand