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Azurophilic granules

Known as: Azurophilic Granule 
A cytoplasmic granule found in the myelocyte lineage that can be stained with azure dyes.
National Institutes of Health

Related topics

Related topics

3 relations
Azurophilic Granule MeasurementLeukocytesLysosomes

Papers overview

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Highly Cited
2015
Highly Cited
2015
Human Neutrophils Secrete Bioactive Paucimannosidic Proteins from Azurophilic Granules into Pathogen-Infected Sputum*
Background: Protein paucimannosylation is considered an important invertebrate- and plant-specific glycoepitope. Results… Expand
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Highly Cited
2010
Highly Cited
2010
Rab27a and Rab27b Regulate Neutrophil Azurophilic Granule Exocytosis and NADPH oxidase Activity by Independent Mechanisms
Neutrophils rely on exocytosis to mobilize receptors and adhesion molecules and to release microbicidal factors. This process… Expand
Highly Cited
2006
Highly Cited
2006
Streptococcus pyogenes bacteria modulate membrane traffic in human neutrophils and selectively inhibit azurophilic granule fusion with phagosomes
We recently reported that the human pathogen Streptococcus pyogenes of the M1 serotype survives and replicates intracellularly… Expand
Highly Cited
2006
Highly Cited
2006
Combinatorial SNARE Complexes Modulate the Secretion of Cytoplasmic Granules in Human Neutrophils1
Mobilization of human neutrophil granules is critical for the innate immune response against infection and for the outburst of… Expand
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Highly Cited
2002
Highly Cited
2002
Secretion of heparin-binding protein from human neutrophils is determined by its localization in azurophilic granules and secretory vesicles.
Human neutrophils have an important role in host defense against microbial infection. At different stages of an infectious… Expand
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Highly Cited
2000
Highly Cited
2000
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation.
A 5-week-old male infant presented with severe bacterial infections and poor wound healing, suggesting a neutrophil defect… Expand
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Highly Cited
1999
Highly Cited
1999
The intracellular serpin proteinase inhibitor 6 is expressed in monocytes and granulocytes and is a potent inhibitor of the azurophilic granule protease, cathepsin G.
The monocyte and granulocyte azurophilic granule proteinases elastase, proteinase 3, and cathepsin G are implicated in acute and… Expand
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Highly Cited
1989
Highly Cited
1989
The opsonizing ligand on Salmonella typhimurium influences incorporation of specific, but not azurophil, granule constituents into neutrophil phagosomes
Phagosomes were purified from human neutrophils ingesting Salmonella typhimurium opsonized with adsorbed normal human serum or… Expand
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Highly Cited
1985
Highly Cited
1985
Evidence for distinct intracellular pools of receptors for C3b and C3bi in human neutrophils.
In this report, the modulation and localization of complement receptors CR1 and CR3 in neutrophils were examined with the use of… Expand
Highly Cited
1983
Highly Cited
1983
Conversion of leukotriene D4 to leukotriene E4 by a dipeptidase released from the specific granule of human polymorphonuclear leucocytes.
Leukotriene D4 (LTD4), the most active spasmogenic leukotriene constituent of the slow reacting substance of anaphylaxis was… Expand
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