Lysosomes

Known as: Lysosoma, Lysosome 
A class of morphologically heterogeneous cytoplasmic membrane-bound vesicle in animal and plant tissues characterized by their content of a wide… (More)

Topic mentions per year

Topic mentions per year

1955-2018
050019552017

Papers overview

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Highly Cited
2010
Highly Cited
2010
Autophagy is an evolutionarily conserved process by which cytoplasmic proteins and organelles are catabolized. During starvation… (More)
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Highly Cited
2006
Highly Cited
2006
We introduce a method for optically imaging intracellular proteins at nanometer spatial resolution. Numerous sparse subsets of… (More)
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Highly Cited
2001
Highly Cited
2001
Plasma membrane wounds are repaired by a mechanism involving Ca(2+)-regulated exocytosis. Elevation in intracellular [Ca(2… (More)
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Highly Cited
2000
Highly Cited
2000
The molecular machinery behind lysosome biogenesis and the maintenance of the perinuclear aggregate of late endocytic structures… (More)
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Highly Cited
1998
Highly Cited
1998
We studied the effects of bafilomycin A1, a potent and specific inhibitor of vacuolar H+ ATPase (V-ATPase), on the process of… (More)
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Highly Cited
1996
Highly Cited
1996
We have followed the transfer of EGF-EGF receptor (EGFR) complexes from endosomal vacuoles that contain transferrin receptors… (More)
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Highly Cited
1996
Highly Cited
1996
Multiple pathways of protein degradation operate within cells. A selective protein import pathway exists for the uptake and… (More)
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Highly Cited
1991
Highly Cited
1991
Cytotoxic T lymphocytes (CTL) contain granules that are exocytosed during specific interaction with target cells (TC). In this… (More)
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Highly Cited
1988
Highly Cited
1988
Localization of the 215 kd mannose 6-phosphate receptor (MPR) was studied in normal rat kidney cells. Low levels of receptor were… (More)
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Highly Cited
1962
Highly Cited
1962
De Duve and his colleagues, a few years ago, originated the concept of lysosomes based on the biochemical analysis of isolated… (More)
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