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Azoxymethane
Known as:
AOM
, Azoxymethane [Chemical/Ingredient]
, Diazene, dimethyl-, 1-oxide
A substance that is used in cancer research to cause colon tumors in laboratory animals. This is done to test new diets, drugs, and procedures for…
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National Institutes of Health
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Related topics
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9 relations
Broader (1)
Carcinogens
In Blood
agonists
analogs & derivatives
antagonists & inhibitors
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Narrower (1)
azoxyethane
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
[In vitro and in vivo effects of mango pulp (Mangifera indica cv. Azucar) in colon carcinogenesis].
Andrea Corrales-Bernal
,
Luz Amparo Urango
,
B. Rojano
,
M. Maldonado
Archivos latinoamericanos de nutrición
2014
Corpus ID: 19625548
Mango pulp contains ascorbic acid, carotenoids, polyphenols, terpenoids and fiber which are healthy and could protect against…
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2007
2007
Aktivitas antioksidan rempah pasar dan bubuk rempah pabrik dengan metode polifenol dan uji Aom (Active oxygen method)
F. Nely
2007
Corpus ID: 81646200
2007
2007
Fauna do solo influenciada pelo uso de fertilizantes minerais e dejetos suínos na sucessão aveia milho, sob semeadura direta
M. V. Alves
2007
Corpus ID: 181380290
O presente estudo objetivou avaliar o efeito da adicao de doses crescentes de dejetos suinos, adubacao combinada dejeto + mineral…
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2001
2001
Differential Effects of CYP 2 E 1 Status on the Metabolic Activation of the Colon Carcinogens Azoxymethane and Methylazoxymethanol 1
O. Sohn
,
E. Fiala
,
Silvia P. Requeijo
,
J. Weisburger
,
F. Gonzalez
2001
Corpus ID: 33920557
Methylazoxymethanol (MAM) and its chemical and metabolic precursor, azoxymethane (AOM), both strong colon carcinogens in rodents…
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1997
1997
Dietary polyamines promote the growth of azoxymethane-induced aberrant crypt foci in rat colon.
J. Paulsen
,
R. Reistad
,
K. A. Eliassen
,
O. Sjaastad
,
J. Alexander
Carcinogenesis
1997
Corpus ID: 18653426
We have examined whether dietary polyamines influence the formation and initial growth of azoxymethane (AOM)-induced aberrant…
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1985
1985
Are animal models of colon cancer relevant to human disease
D. Ahnen
Digestive Diseases and Sciences
1985
Corpus ID: 7731454
Since its original description by Druckrey (1), the rodent model of colon cancer induced with i,2dimethylhydrazine has become…
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1981
1981
Effect of inhibitors of tumorigenesis on the formation of O6-methylguanine in the colon of 1,2-dimethylhydrazine-treated rats.
Arthur W. Bull
,
Adrian D. Burd
,
Norman D. Nigro
Cancer Research
1981
Corpus ID: 10417122
The level of O6-methylguanine (O6MeGua) in the colonic DNA of rats treated with 1,2-dimethylhydrazine was determined. The effect…
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1978
1978
Rat liver microsome-mediated N-demethylation and mutagenicity of azoxymethane.
R. Campbell
,
John D. Suppnick
,
Joanne M. Hettrick
,
Norman D. Nigro
Cancer Research
1978
Corpus ID: 10826141
Abstract The in vitro metabolism of azoxymethane (AOM), a highly specific intestinal carcinogen, was studied. Liver microsomes…
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1977
1977
Inhibition of 1,2-dimethylhydrazine metabolism by disulfiram.
Emerich S. Fiala
,
George Bobotas
,
Callie Kulakis
,
J. Weisburger
Xenobiotica; the fate of foreign compounds in…
1977
Corpus ID: 1321304
1. The effects of disulfiram on the metabolism of 1,2-dimethylhydrazine were studied in CDF rats. 2. Treatment with disulfiram…
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1976
1976
Effect of diet high in beef fat on the composition of fecal bile acids during intestinal carcinogenesis in the rat.
Norman D. Nigro
,
R. Campbell
,
Dharm V. Singh
,
Y. N. Lin
Journal of the National Cancer Institute
1976
Corpus ID: 29618424
Two groups of 20 male Sprague-Dawley rats each were given sc 8 mg azoxymethane/kg body weight and fed a normal diet or one high…
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