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Arachidonate 12-Lipoxygenase

Known as: Arachidonic Acid 12-Lipoxygenase, Arachidonate 12 Lipoxygenase, 12-Lipoxygenase, Arachidonate 
An enzyme that catalyzes the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-HPETE) which is itself rapidly converted by a… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Histamine provokes itching and is a major skin disease complaint. Histamine is known to excite a subset of sensory neurons… Expand
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Highly Cited
2006
Highly Cited
2006
Roots and stem-bark of Mahonia aquifolium (Oregon grape) (Berberidaceae) are effectively used in the treatment of skin… Expand
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Highly Cited
2003
Highly Cited
2003
Vitamin E is a generic term for tocopherols and tocotrienols. This work is based on our striking evidence that, in neuronal cells… Expand
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Highly Cited
2002
Highly Cited
2002
Extensive studies have implicated the role of dietary fatty acids in prostatecancer progression. Platelet-type 12-Lipoxygenase… Expand
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Highly Cited
2000
Highly Cited
2000
Treatment of human artery wall cells with apolipoprotein A-I (apoA-I), but not apoA-II, with an apoA-I peptide mimetic, or with… Expand
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Highly Cited
2000
Highly Cited
2000
Angiogenesis, the formation of new capillaries from preexisting blood vessels, is a multistep, highly orchestrated process… Expand
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Highly Cited
1997
Highly Cited
1997
An early and highly specific decrease in glutathione (GSH) in the substantia nigra is associated with Parkinson's disease, and… Expand
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Review
1995
Review
1995
In the last decade our laboratory has been investigating arachidonate 12-lipoxy-genase intensively and extensively.1.2 The enzyme… Expand
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Highly Cited
1992
Highly Cited
1992
Isomers (alpha- and beta-) of boswellic acids (BAs), 11-keto-beta-BA and their acetyl derivatives were isolated from the gum… Expand
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Highly Cited
1989
Highly Cited
1989
L-663,536 (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2, 2-dimethylpropanoic acid) is a potent inhibitor of… Expand
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