Arachidonate 12-Lipoxygenase

Known as: Arachidonic Acid 12-Lipoxygenase, Arachidonate 12 Lipoxygenase, 12-Lipoxygenase, Arachidonate 
An enzyme that catalyzes the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-HPETE) which is itself rapidly converted by a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2017
024619822017

Papers overview

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2010
2010
CONTEXT Inflammation is increasingly recognized as an important contributing factor in diabetes mellitus. Lipoxygenases (LOs… (More)
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2008
2008
Inflammation is a key pathological process in the progression of atherosclerosis and type 2 diabetes. 12/15-lipoxygenase (12-LO… (More)
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2006
2006
12-Lipoxygenase utilizes arachidonic acid to synthesize 12(S)-hydroperoxyeicosatetraenoic acid, which is converted to the end… (More)
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Highly Cited
2002
Highly Cited
2002
Extensive studies have implicated the role of dietary fatty acids in prostatecancer progression. Platelet-type 12-Lipoxygenase… (More)
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2001
2001
Arachidonic acid release from membrane phospholipids is essential for tumour cell proliferation. Lipoxygenases constitute a… (More)
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2001
2001
BACKGROUND 12-Lipoxygenase (12-LO) products of arachidonate metabolism have growth and chemotactic effects in vascular smooth… (More)
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1995
1995
Arachidonate 12-lipoxygenase is an enzyme that oxygenates the 12 position of arachidonic acid to produce its 12-hydroperoxy… (More)
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1994
1994
12(S)-Hydroxyeicosatetraenoic acid [12(S)-HETE] is the 12-lipoxygenase metabolite of arachidonic acid. Previously, we have… (More)
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1993
1993
12-Lipoxygenase oxygenates the 12 position of arachidonic acid, producing its 12S-hydroperoxy derivative. We have been interested… (More)
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1992
1992
The cytosol fraction from a thoroughly irrigated canine cerebrum was subjected to immunoaffinity chromatography using a… (More)
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