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ALOX12 gene

Known as: ARACHIDONATE 12-OXIDOREDUCTASE, platelet 12-LOX, 12LO 
This gene plays a role in oxidation of fatty acids.
National Institutes of Health

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ALOX12 wt Allele
Arachidonate 12-LipoxygenaseArachidonate 12-Lipoxygenase, 12S-TypeLeukotriene ProductionOxidation-Reduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Polymorphisms in ALOX12, but not ALOX15, Are Significantly Associated With BMD in Postmenopausal Women
The murine arachidonate 15-lipoxygenase gene (Alox15) has recently been identified as a negative regulator of peak bone mineral… 
Highly Cited
1993
Highly Cited
1993
Molecular cloning of a 12-lipoxygenase cDNA from rat brain.
A cDNA encoding an arachidonate 12-lipoxygenase from rat brain was obtained by polymerase chain reaction cloning. Primers… 
Highly Cited
1993
Highly Cited
1993
Investigation of the oxygenation of phospholipids by the porcine leukocyte and human platelet arachidonate 12-lipoxygenases.
When arachidonate 12-lipoxygenase purified from porcine leukocytes was incubated aerobically with 1-palmitoyl-2-arachidonoyl-sn… 
Highly Cited
1993
Highly Cited
1993
Structure‐function properties of human platelet 12‐lipoxygenase: chimeric enzyme and in vitro mutagenesis studies
Mutant and chimeric lipoxygenases were expressed in human embryonal kidney 293 cells to assess the importance of amino acids and… 
1992
1992
Molecular structure and function of the porcine arachidonate 12-lipoxygenase gene.
Highly Cited
1990
Highly Cited
1990
Molecular cloning and expression of human arachidonate 12-lipoxygenase.
Highly Cited
1990
Highly Cited
1990
Identification of a novel arachidonate 12-lipoxygenase in bovine tracheal epithelial cells distinct from leukocyte and platelet forms of the enzyme.
1987
1987
Lipoxin synthesis by arachidonate 12-lipoxygenase purified from porcine leukocytes.
1986
1986
Studies on porcine arachidonate 12-lipoxygenase using its monoclonal antibodies.
Monoclonal antibodies were raised against arachidonate 12-lipoxygenase using a partially purified enzyme from porcine leukocytes… 
1983
1983
Partial purification and characterization of arachidonate 12-lipoxygenase from rat lung.
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