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ALOX12 gene
Known as:
ARACHIDONATE 12-OXIDOREDUCTASE
, platelet 12-LOX
, 12LO
Â
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This gene plays a role in oxidation of fatty acids.
Topic mentions per year
Topic mentions per year
1982-2018
0
5
10
1982
2018
Related topics
Related topics
6 relations
Narrower (1)
ALOX12 wt Allele
Arachidonate 12-Lipoxygenase
Arachidonate 12-Lipoxygenase, 12S-Type
Leukotriene Production
Oxidation-Reduction
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Related mentions per year
Related mentions per year
1936-2018
1940
1960
1980
2000
2020
ALOX12 gene
Oxidation-Reduction
fatty acid metabolism
ALOX12 wt Allele
Arachidonate 12-Lipoxygenase, 12S-Type
Arachidonate 12-Lipoxygenase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
RUNX1/core binding factor A2 regulates platelet 12-lipoxygenase gene (ALOX12): studies in human RUNX1 haplodeficiency.
Gurpreet Kaur
,
Gauthami S. Jalagadugula
,
Guangfen Mao
,
A. Koneti Rao
Blood
2010
Haploinsufficiency of RUNX1 (also known as CBFA2/AML1) is associated with familial thrombocytopenia, platelet dysfunction, and…Â
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2010
2010
ALOX12 gene is associated with the onset of natural menopause in white women.
Pengyuan Liu
,
Yan Lu
,
Robert Roy Recker
,
Hong-Wen Deng
,
Volodymyr Dvornyk
Menopause
2010
OBJECTIVE Natural menopause is a key physiological event in a woman's life. Timing of menopause affects risk for many…Â
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2008
2008
Induction of arachidonate 12-lipoxygenase (Alox15) in intestine of iron-deficient rats correlates with the production of biologically active lipid mediators.
James F Collins
,
Zihua Hu
,
+4 authors
Richard W. Browne
American journal of physiology. Gastrointestinal…
2008
To identify novel genes associated with iron metabolism, we performed gene chip studies in two models of iron deficiency: iron…Â
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2006
2006
Human ALOX12, but not ALOX15, is associated with BMD in white men and women.
Shoji Ichikawa
,
Daniel L. Koller
,
+9 authors
Michael J. Econs
Journal of bone and mineral research : the…
2006
UNLABELLED The Alox15 gene was recently identified as a negative regulator of peak BMD in mice. Polymorphisms in human ALOX12…Â
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2005
2005
Activation of 12-lipoxygenase in proinflammatory cytokine-mediated beta cell toxicity
Mukai Chen
,
Z. D. Yang
,
K. M. Smith
,
Jeffery D. Carter
,
Jeffrey Nadler
Diabetologia
2005
Beta cell inflammation and cytokine-induced toxicity are central to autoimmune diabetes development. Lipid mediators generated…Â
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2003
2003
Association of a new polymorphism in ALOX12 gene with bipolar disorder
Cintia Fridman
,
Élida P. B. Ojopi
,
+7 authors
Emmanuel Dias Neto
European Archives of Psychiatry and Clinical…
2003
Bipolar disorder (BPD) is characterised by episodes of excitement interspersed with periods of depression. The role of genetic…Â
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2001
2001
Adenoviral delivery of a leukocyte-type 12 lipoxygenase ribozyme inhibits effects of glucose and platelet-derived growth factor in vascular endothelial and smooth muscle cells.
M K Patricia
,
R. Natarajan
,
+7 authors
Catherine C. Hedrick
Circulation research
2001
The lipoxygenase (LO) pathway has been implicated as an important mediator of chronic glucose and platelet-derived growth factor…Â
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1994
1994
Oxidative modification of human lipoproteins by lipoxygenases of different positional specificities.
Harmut Kühn
,
Jutta Belkner
,
H. Suzuki
,
S. Yamamoto
Journal of lipid research
1994
Cellular lipoxygenases have been implicated in foam cell formation during the early stages of atherogenesis. We studied the…Â
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1993
1993
Molecular cloning of a 12-lipoxygenase cDNA from rat brain.
T. Watanabe
,
Jesús Medina
,
Jesper Z. Haeggström
,
Olof RÃ¥dmark
,
Bengt O Samuelsson
European journal of biochemistry
1993
A cDNA encoding an arachidonate 12-lipoxygenase from rat brain was obtained by polymerase chain reaction cloning. Primers…Â
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1990
1990
Cloning and sequence analysis of the cDNA for arachidonate 12-lipoxygenase of porcine leukocytes.
Tetsuro Yoshimoto
,
H. Suzuki
,
S. Yamamoto
,
T. Takai
,
Christine C. Yokoyama
,
Tsuyoshi Tanabe
Proceedings of the National Academy of Sciences…
1990
The complete amino acid sequence of arachidonate 12-lipoxygenase (EC 1.13.11.31) of porcine leukocytes was deduced by cloning and…Â
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