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ALOX12 gene

Known as: ARACHIDONATE 12-OXIDOREDUCTASE, platelet 12-LOX, 12LO 
This gene plays a role in oxidation of fatty acids.
National Institutes of Health

Papers overview

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2018
2018
Hepatic ischemia–reperfusion (IR) injury is a common clinical issue lacking effective therapy and validated pharmacological… Expand
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Highly Cited
2010
Highly Cited
2010
Haploinsufficiency of RUNX1 (also known as CBFA2/AML1) is associated with familial thrombocytopenia, platelet dysfunction, and… Expand
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Highly Cited
2006
Highly Cited
2006
12-Lipoxygenase utilizes arachidonic acid to synthesize 12(S)-hydroperoxyeicosatetraenoic acid, which is converted to the end… Expand
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Highly Cited
2005
Highly Cited
2005
A complex mixture of fatty acid-derived aldehydes, ketones, and alcohols is released upon wounding of the moss Physcomitrella… Expand
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Highly Cited
2005
Highly Cited
2005
Aims/hypothesisBeta cell inflammation and cytokine-induced toxicity are central to autoimmune diabetes development. Lipid… Expand
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Highly Cited
2000
Highly Cited
2000
Angiogenesis, the formation of new capillaries from preexisting blood vessels, is a multistep, highly orchestrated process… Expand
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Highly Cited
1998
Highly Cited
1998
Previously, we found a positive correlation between the expression of platelet-type 12-lipoxygenase (12-LOX) and the progression… Expand
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Highly Cited
1994
Highly Cited
1994
Cellular lipoxygenases have been implicated in foam cell formation during the early stages of atherogenesis. We studied the… Expand
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1992
1992
The immunohistochemical distribution of arachidonate lipoxygenases in rat pancreas was characterized with specific polyclonal… Expand
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1990
1990
The complete amino acid sequence of arachidonate 12-lipoxygenase (EC 1.13.11.31) of porcine leukocytes was deduced by cloning and… Expand
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