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Apolipoprotein E4

Known as: Apolipoprotein E 4, Apo E epsilon 4, NP_000032.1:p.Cys130Arg 
A major and the second most common isoform of apolipoprotein E. In humans, Apo E4 differs from APOLIPOPROTEIN E3 at only one residue 112 (cysteine is… 
National Institutes of Health

Related topics

Related topics

22 relations
APOE*4 AlleleAlzheimer's DiseaseAlzheimer's Disease Pathway KEGGApolipoprotein E4:PrThr:Pt:Bld:Ord

Narrower (2)

apolipoprotein E4 (Freiburg)apolipoprotein E4 (Philadelphia)

Papers overview

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Highly Cited
2008
Highly Cited
2008
Rapid incorporation of functional rhodopsin into nanoscale apolipoprotein bound bilayer (NABB) particles.
Highly Cited
1999
Highly Cited
1999
Tear lipocalins: potential lipid scavengers for the corneal surface.
PURPOSE To investigate the dynamic effect of tear lipocalins (TLs), the major lipid-binding protein in tears, at aqueous-cornea… 
Highly Cited
1998
Highly Cited
1998
Differential Cellular Accumulation/Retention of Apolipoprotein E Mediated by Cell Surface Heparan Sulfate Proteoglycans
Isoform-specific effects of apolipoprotein E (apoE) on neurite outgrowth and the cytoskeleton are associated with higher… 
Highly Cited
1996
Highly Cited
1996
Sphingomyelin Inhibits the Lecithin-Cholesterol Acyltransferase Reaction with Reconstituted High Density Lipoproteins by Decreasing Enzyme Binding*
Lecithin-cholesterol acyltransferase (LCAT) catalyzes the formation of cholesterol esters on high density lipoproteins (HDL) and… 
Highly Cited
1995
Highly Cited
1995
Decreased hippocampal volume asymmetry on MRIs in nondemented elderly subjects carrying the apolipoprotein E ϵ4 allele
1. Levin MJ, Gardner P, Waldvogel F. “Tropical” pyomyositis, an unusual infection due to Staphylococcus aureus. N Engl J Med 1971… 
Highly Cited
1995
Highly Cited
1995
Arginine residues at codons 112 and 158 in the apolipoprotein E gene correspond to the ancestral state in humans.
Highly Cited
1983
Highly Cited
1983
Linkage of human apolipoproteins A-I and C-III genes
It has recently been suggested that polymorphisms in the human apolipoprotein A-I (apo A-I) gene locus may be related to the… 
Highly Cited
1983
Highly Cited
1983
An inherited polymorphism in the human apolipoprotein A-I gene locus related to the development of atherosclerosis
Epidemiological studies have identified elevated low density lipoprotein (LDL)1–3 and diminished high density lipoprotein (HDL… 
Highly Cited
1978
Highly Cited
1978
ALTERATIONS IN HUMAN HIGH-DENSITY LIPOPROTEINS, WITH OR WITHOUT INCREASED PLASMA-CHOLESTEROL, INDUCED BY DIETS HIGH IN CHOLESTEROL
Highly Cited
1976
Highly Cited
1976
Measurement of human high density lipoprotein apolipoprotein A-1 in serum by radioimmunoassay.
A sensitive and specific double antibody radioimmunoassay for the major apolipoprotein (apo A-I) of human serum high density… 
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