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Anvirzel

 
National Institutes of Health

Papers overview

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2012
2012
BackgroundPlatinum derivatives are used widely for the treatment of many cancers. However, the toxicity that is observed makes… Expand
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2011
2011
Recent studies revealed the potential of Na(+)/K(+)-ATPase as a target for anticancer therapy and showed additional modes of… Expand
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Highly Cited
2006
Highly Cited
2006
SummaryAnvirzelTM is an aqueous extract of the plant Nerium oleander which has been utilized to treat patients with advanced… Expand
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Review
2006
Review
2006
The well known and accepted mode of action of cardiac glycosides is inhibition of the ubiquitous plasma membrane Na+, K+-ATPase… Expand
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2002
2002
Cardiac glycosides such as digitoxin and ouabain have previously been shown to be selectively cytotoxic to tumor as opposed to… Expand
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2002
2002
Pharmacokinetic studies of [3H]oleandrin, a cardiac glycoside component of Anvirzel, were conducted in mice after either an i.v… Expand
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Highly Cited
2001
Highly Cited
2001
Anvirzel is an extract of Nerium oleander currently undergoing Phase I clinical evaluation as a potential treatment for cancer… Expand
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Highly Cited
2000
Highly Cited
2000
Agents that can suppress the activation of nuclear factor-kappaB (NF-kappaB) and activator protein-1 (AP-1) may be able to block… Expand
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Highly Cited
2000
Highly Cited
2000
The purpose of this study was to examine the mechanism(s) and differential cell-killing effects of AnvirzelTM, an extract of… Expand
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2000
2000
An HPLC/MS/MS method has been developed for the characterization and quantification of the cardiac glycosides oleandrin… Expand
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